Lactobacillus plantarum 299v and Reduced Bloating

• Role of Lactobacillus plantarum 299v versus Placebo in symptomatic improvement of irritable bowel syndrome patients.

  • 2022-02-03
  • RCT · n = 190
  • JPMA. The Journal of the Pakistan Medical Association 72(3)
  • • Ahmad Nawaz Babar
    • Muhammad Kamran Hassan
    • Fazl Ullah
    • Anwar Ullah

  • PubMed: 35320214
  • DOI: 10.47391/jpma.0758

  5 Insights on

  • Reduced Bloating

  • High evidence
  • Large Human Trial

  There was no significant difference in terms of relieving abdominal pain, bloating and rectal emptying between the groups (p>0.05).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• Probiotics in foods not containing milk or milk constituents, with special reference to Lactobacillus plantarum 299v.

  • 2001-02
  • The American Journal of Clinical Nutrition 73(2)
  • • G. Molin

  • PubMed: 11157345
  • DOI: 10.1093/ajcn/73.2.380s

  4 Insights on

  • Reduced Bloating

  • Low evidence
  • Highly Cited

  In humans, L. plantarum 299v can increase the concentration of carboxylic acids in feces and decrease abdominal bloating in patients with irritable bowel disease.

  Effect

  Beneficial

  Effect size

  Moderate

  Dose

  5 x 10^10 colony-forming units/L