Lactobacillus reuteri MAK02L14R and Improved Insulin Sensitivity

• Lactobacillus reuteri J1 prevents obesity by altering the gut microbiota and regulating bile acid metabolism in obese mice.

  • 2022-06-22
  • Clinical Trial
  • Food & Function 13(12)
  • • Chenxi Zhang
    • Ru-Ying Fang
    • Xing Lu
    • Yu Zhang
    • Mo Yang
    • Yue Su
    • Yujun Jiang
    • C. Man

  • PubMed: 35647914
  • DOI: 10.1039/d1fo04387k

  10 Insights on

  • Improved Insulin Sensitivity

  • Low evidence
  • Animal Study

  The results revealed that L. reuteri J1 prevented weight gain, lowered fat mass and relieved dyslipidemia, and improved glucose homeostasis and insulin sensitivity.

  Effect

  Beneficial

  Effect size

  Large

• Heat-killed and live Lactobacillus reuteri GMNL-263 exhibit similar effects on improving metabolic functions in high-fat diet-induced obese rats.

  • 2018-02-16
  • Clinical Trial
  • Food & Function 7(5)
  • • Feng-Ching Hsieh
    • C. Lan
    • Tsui-Yin Huang
    • Kuan-Wei Chen
    • C. Chai
    • Wan-Tzu Chen
    • Ai-Hui Fang
    • Yi-Hsing Chen
    • Ching-Shuang Wu

  • PubMed: 27163114
  • DOI: 10.1039/c5fo01396h

  24 Insights on

  • Improved Insulin Sensitivity

  • Low evidence
  • Animal Study

  The insulin resistance associated gene expressions in both adipose and hepatic tissues, which were downregulated in the HFD group, were markedly enhanced after HK or live Lr263 administration.

  Effect

  Beneficial

  Effect size

  Large