Lactobacillus rhamnosus GG and Reduced High-Sensitivity C-Reactive Protein Level

Doses used in studies

CFU/day: 1 million–12 billion (median 6.0 billion, IQR 3.0 billion–9.0 billion) — 2 studies

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 2 of 2 studies

2 of 2 papers

A randomized double-blind controlled clinical trial demonstrating efficacy of different probiotic strains on serum lipids and glycemic biomarker.

2024-08-01
RCT · n = 51
Nutricion hospitalaria 41(4)
- Gözde Okburan
- Murat Baş
- Sultan Ogmen

PubMed: 38967303
DOI: 10.20960/nh.04724

5 Insights on

Reduced High-Sensitivity C-Reactive Protein Level

High evidence
Clinical

Also, hs-CRP levels was assessed as inflammatory parameter.

Effect: Neutral
Effect size: Small
Significant: No
Dose: 1 × 10^6 CFU/day

Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals.

2018-08-01
Clinical Trial · n = 45
Journal of acquired immune deficiency syndromes (1999) 78(4)
- Caroline J Arnbjerg
- Beate Vestad
- Johannes R Hov
- Karin K Pedersen
- Sofie Jespersen
- Helle H Johannesen
- Kristian Holm
- Bente Halvorsen
- Eva Fallentin
- Adam E Hansen
- Theis Lange
- Andreas Kjær
- Marius Trøseid
- Barbara M Fischer
- Susanne D Nielsen

PubMed: 29874201
DOI: 10.1097/qai.0000000000001693

11 Insights on

Reduced High-Sensitivity C-Reactive Protein Level

High evidence
Clinical

No changes were observed for soluble markers of microbial translocation and inflammation (lipopolysaccharide, sCD14, sCD163, sCD25, high-sensitive CRP, IL-6, and tumor necrosis factor-alpha)

Effect: Neutral
Effect size: Small
Significant: No
Dose: 6 × 10^9 colony-forming units per capsule twice daily