Nutraceuticals and Pain Disorders of the Gut-Brain Interaction in Infants and Children: A Narrative Review and Practical Insights.
- 2024-01-25
- Review
- Nutrients 16(3)
- Silvia Salvatore
- Mariagrazia Carlino
- Simona Sestito
- Daniela Concolino
- Massimo Agosti
- Licia Pensabene
- PubMed: 38337634
- DOI: 10.3390/nu16030349
- Moderate evidence
- Rigorous Journal
- Clinical
To date, there is moderate-certainty evidence with a weak grade of recommendation on Lactobacillus reuteri DSM 17938 (10^8 CFU/day) in reducing pain intensity in children with functional abdominal pain
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 1-3 × 10^9 CFU twice daily