Best Supplements for Reduced Pain Intensity
Ranked by research evidence. Compare 35 supplements across 45 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence3 studies
Across 3 studies, 2 reported beneficial moderate-sized effects on reducing pain intensity, while 1 found no significant difference. The evidence is strongest in children following tonsillectomy (meta-analysis of 710 participants). Median study duration was 11 days. No consistent dose or form data was reported.
- Low evidence3 studies
Across 3 studies, 1 reported a beneficial large-sized effect of ginger on reducing pain intensity in primary dysmenorrhea, while 2 studies found neutral (no significant) effects in other populations. The predominant effect is mixed, with the strongest evidence coming from a meta-analysis reporting significant pain relief (WMD=2.902, 95% CI 2.039-3.765) in 647 dysmenorrhea patients. The median study duration was 14 days, but the evidence base is small and heterogeneous.
- ModerateHoneyAcross 3 studies, 2 reported beneficial moderate-sized effects on reducing pain intensity, while 1 found no significant difference. The evidence is strongest in children following tonsillectomy (meta-analysis of 710 participants). Median study duration was 11 days. No consistent dose or form data was reported.2 beneficial1 neutral3 studies
- LowGingerAcross 3 studies, 1 reported a beneficial large-sized effect of ginger on reducing pain intensity in primary dysmenorrhea, while 2 studies found neutral (no significant) effects in other populations. The predominant effect is mixed, with the strongest evidence coming from a meta-analysis reporting significant pain relief (WMD=2.902, 95% CI 2.039-3.765) in 647 dysmenorrhea patients. The median study duration was 14 days, but the evidence base is small and heterogeneous.1 beneficial2 neutral3 studies