Lactobacillus rhamnosus R0343ND and Improved Immune Response

• Dietary Lactobacillus rhamnosus GG Supplementation Improves the Mucosal Barrier Function in the Intestine of Weaned Piglets Challenged by Porcine Rotavirus

  • 2016-01-04
  • RCT
  • PLOS ONE 11(1)
  • • X. Mao
    • Changsong Gu
    • Haiyan Hu
    • Jun Tang
    • Daiwen Chen
    • B. Yu
    • Jun He
    • Jie Yu
    • Junqiu Luo
    • G. Tian

  • PubMed: 26727003
  • DOI: 10.1371/journal.pone.0146312

  18 Insights on

  • Improved Immune Response

  • High evidence
  • Highly Cited
  • Rigorous Journal

  Dietary LGG supplementation alleviated the increase of diarrhea rate in the weaned pigs challenged by RV (P<0.05), and relieve the effect of RV infection on the ... IL-2, IL-4, mucin 1 and mucin 2 concentrations of jejunal mucosa (P<0.05)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Fermented milk with probiotic Lactobacillus rhamnosus S1K3 (MTCC5957) protects mice from salmonella by enhancing immune and nonimmune protection mechanisms at intestinal mucosal level.

  • 2016-04
  • Clinical Trial
  • The Journal of Nutritional Biochemistry 30
  • • T. S. Kemgang
    • S. Kapila
    • V. P. Shanmugam
    • S. Reddi
    • R. Kapila

  • PubMed: 27012622
  • DOI: 10.1016/j.jnutbio.2015.11.018

  14 Insights on

  • Improved Immune Response

  • Low evidence
  • Animal Study

  The probiotic induced TLRs transcripts at the Peyer's patches, followed by an increase in the Secretory-IgA in intestinal fluid, the IgA-secreting cells in lamina propria of small intestine and the IgA level in serum.

  Effect

  Beneficial

  Effect size

  Large

• Development of a fermented goats' milk containing Lactobacillus rhamnosus: in vivo study of health benefits.

  • 2011-05-20
  • Clinical Trial
  • Journal of the Science of Food and Agriculture 91(13)
  • • S. Salva
    • M. Núñez
    • J. Villena
    • A. Ramón
    • G. Font
    • S. Alvarez

  • PubMed: 21604277
  • DOI: 10.1002/jsfa.4467

  12 Insights on

  • Improved Immune Response

  • Low evidence
  • Highly Cited
  • Animal Study

  L. rhamnosus CRL1505, a strain of goats' milk origin, is able to stimulate mucosal immunity and protect immunocompetent mice from intestinal and respiratory infections.

  Effect

  Beneficial

  Effect size

  Large