Lactobacillus rhamnosus and Reduced Adipogenesis

• Microbiome, Potential Therapeutic Agents: New Players of Obesity Treatment.

  • 2025-04-24
  • Review
  • Journal of microbiology and biotechnology 35
  • • Maqsood Ali
    • Navid Iqbal
    • Md Abdur Rakib
    • Kyung-Ah Lee
    • Mi-Hwa Lee
    • Yong-Sik Kim

  • PubMed: 40295195
  • DOI: 10.4014/jmb.2501.01024

  3 Insights on

  • Reduced Adipogenesis

  • Low evidence

  The microbiome impacts adipogenesis through lipogenesis and inflammation pathways and influences adipose tissue browning via the secretion of gut hormones and short-chain fatty acids.

  Effect

  Beneficial

  Effect size

  Small

• Multifunctional Probiotic and Functional Properties of Lactiplantibacillus plantarum LRCC5314, Isolated from Kimchi

  • 2022-01-28
  • Journal of Microbiology and Biotechnology 32(1)
  • • Seokmin Yoon
    • H. Cho
    • YoHan Nam
    • Mi-ri Park
    • Ahyoung Lim
    • Jong-Hwa Kim
    • Jaewoong Park
    • Wonyong Kim

  • PubMed: 34750286
  • DOI: 10.4014/jmb.2109.09025

  11 Insights on

  • Reduced Adipogenesis

  • Low evidence

  LRCC5314 also inhibited adipogenesis in differentiating preadipocytes (3T3-L1 cells), showing a 14.7% decrease in lipid droplet levels and a 74.0% decrease in triglyceride levels, as well as distinct reductions in the mRNA expression levels of adiponectin, FAS, PPAR/γ, C/EBPα, TNF-α, and IL-6.

  Effect

  Beneficial

  Effect size

  Large