Lactobacillus salivarius UALb-07 and Reduced Inflammatory Response

• Effect of Probiotic Lactobacillus salivarius UBL S22 and Prebiotic Fructo-oligosaccharide on Serum Lipids, Inflammatory Markers, Insulin Sensitivity, and Gut Bacteria in Healthy Young Volunteers

  • 2014-10-20
  • RCT · n = 45
  • Journal of Cardiovascular Pharmacology and Therapeutics 20(3)
  • • H. Rajkumar
    • Manoj Kumar
    • Nilita Das
    • Subramanian Hari Subbish Kumar
    • Hanumanth R. Challa
    • R. Nagpal

  • PubMed: 25331262
  • DOI: 10.1177/1074248414555004

  12 Insights on

  • Reduced Inflammatory Response

  • High evidence
  • Highly Cited

  Similarly, when compared to the placebo group, the serum concentrations of inflammatory markers such as high sensitivity C-reactive protein, interleukin (IL) 6, IL-1β, and tumor necrosis factor α were significantly (P < .05) reduced in both the experimental groups, but again the reduction in the synbiotic group was more pronounced.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Lactic acid-mediated suppression of Helicobacter pylori by the oral administration of Lactobacillus salivarius as a probiotic in a gnotobiotic murine model

  • 1998-11
  • American Journal of Gastroenterology 93(11)
  • • Y. Aiba
    • Nobuyuki Suzuki
    • A. M. Kabir
    • A. Takagi
    • Y. Koga

  • PubMed: 9820379
  • DOI: 10.1111/j.1572-0241.1998.00600.x

  2 Insights on

  • Reduced Inflammatory Response

  • Low evidence
  • Highly Cited

  The validity of L. salivarius as a probiotic to suppress H. pylori and thus reduce the inflammatory response was again confirmed in vivo by using an H. pylori-infected gnotobiotic murine model.

  Effect

  Beneficial

  Effect size

  Large