Lactobacillus and Improved Intestinal Barrier Function

• Lactobacillus combination alleviates dextran sulfate sodium-induced colitis in Wuzhishan minipigs.

  • 2026-04-14
  • Food & function 17(7)
  • • Xiaozhe Wang
    • Xiangyu Ma
    • Xin Zhang
    • Yang He
    • Yinfeng Chen
    • Qingyao Fu
    • Ying Yang
    • Xiaomin Yin
    • Zhenlong Wu

  • PubMed: 41860415
  • DOI: 10.1039/d4fo04728a

  4 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Rigorous Journal
  • Animal Study

  ...while increasing the expression levels of tight junction protein zonula occludens-1 (ZO-1) and mucin 1 (MUC1).

  Effect

  Beneficial

  Effect size

  Moderate

• The role of Lactobacillus in dibutyl phthalate-induced gut and liver injury: Probiotic intervention and multi-omics evidence.

  • 2026-04
  • Ecotoxicology and environmental safety 314
  • • Siming Huo
    • Bo Li
    • Jiayu Du
    • Zheng Cao

  • PubMed: 41895142
  • DOI: 10.1016/j.ecoenv.2026.120051

  2 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Animal Study

  Intervention with LGG significantly ameliorated both intestinal barrier dysfunction (restored tight junctions, reduced permeability) and hepatic injury (attenuated steatosis, oxidative stress, and inflammation).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes