Lactobacillus and Reduced Caries Severity

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
The intervention was well tolerated, with no adverse events reported and high participant acceptability.
from: Effects of Probiotic Short-Term Regiment on Oral Health Parameters in Children: A Pilot Ra

1 of 1 paper

Effects of Probiotic Short-Term Regiment on Oral Health Parameters in Children: A Pilot Randomized Controlled Trial.

2025-11-18
RCT · n = 40
Nutrients 17(22)
- Edouard Starck
- Vanessa Machado
- João Botelho
- Luís Proença
- Helena Barroso
- Carla Ascenso
- Cecília Rozan

PubMed: 41305654
DOI: 10.3390/nu17223604

6 Insights on

Reduced Caries Severity

High evidence
Rigorous Journal
Children

Despite there being no statistically significant differences in any clinical or microbiological parameter (p > 0.05), we found trends toward higher salivary pH, improved buffering capacity, and reduced S. mutans counts in the probiotic group.

Effect: Neutral
Effect size: Small
Significant: No