Pediococcus pentosaceus KABP-041 and Improved Intestinal Barrier Function

• Pediococcus pentosaceus PR-1 modulates high-fat-died-induced alterations in gut microbiota, inflammation, and lipid metabolism in zebrafish

  • 2023-02-01
  • Clinical Trial
  • Frontiers in Nutrition 10
  • • Yue Liu
    • D-L Zhu
    • Jiwen Liu
    • X. Sun
    • Feng Gao
    • Hui-Ping Duan
    • Lina Dong
    • Xin Wang
    • Changxing Wu

  • PubMed: 36819708
  • DOI: 10.3389/fnut.2023.1087703

  15 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Animal Study

  Probiotic also ameliorated gut barrier function by increasing the expressions of occludin, Claudin-1, and ZO-1.

  • Beneficial
  • Moderate effect

• New strain of Pediococcus pentosaceus alleviates ethanol-induced liver injury by modulating the gut microbiota and short-chain fatty acid metabolism

  • 2020-10-28
  • RCT · n = 28
  • World Journal of Gastroenterology 26(40)
  • • Xianwan Jiang
    • Yating Li
    • Jian-zhong Ye
    • L. Lv
    • Liya Yang
    • Xiaoyuan Bian
    • Wen-rui Wu
    • Jingjing Wu
    • D. Shi
    • Qing Wang
    • D. Fang
    • Kaicen Wang
    • Qiangqiang Wang
    • Yanmeng Lu
    • Jiaojiao Xie
    • Lanjuan Li

  • PubMed: 33177795
  • DOI: 10.3748/wjg.v26.i40.6224

  9 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Rigorous Journal
  • Animal Study

  Furthermore, the levels of the tight junction protein ZO-1, mucin proteins (mucin \\[MUC\\]-1, MUC-2 and MUC-4) and the antimicrobial peptide Reg3β were increased after probiotic supplementation.

  • Beneficial
  • Large effect