Anti-colorectal cancer activity of mannatide from spent brewer's yeast by regulating immune cells and immune function in the tumor microenvironment.
- 2024-11
- International journal of biological macromolecules 280
- Fei Li
- Xiaopeng Sun
- Xiang Gao
- Shuang Zhao
- Samad Tavakoli
- Zubo Du
- Yuxi Wei
- PubMed: 39270895
- DOI: 10.1016/j.ijbiomac.2024.135531
- Low evidence
MTE treatment reshaped tumor-associated macrophages (TAMs) from alternatively activated macrophages (M2)-like into classical activated macrophages (M1)-like phenotype. Also, it increased the proportion of CD8+ and CD4+ T cells
- Effect
- Beneficial
- Effect size
- Large