Saccharomyces cerevisiae and Improved Immune Function

• Enhancing immunity in viral infections, with special emphasis on COVID-19: A review.

  • 2020-07
  • Systematic Review · n = 640
  • Diabetes & metabolic syndrome 14(4)
  • • Ranil Jayawardena
    • Piumika Sooriyaarachchi
    • Michail Chourdakis
    • Chandima Jeewandara
    • Priyanga Ranasinghe

  • PubMed: 32334392
  • DOI: 10.1016/j.dsx.2020.04.015

  2 Insights on

  • Improved Immune Function

  • High evidence
  • Highly Cited

  Several nutraceuticals and probiotics may also have some role in enhancing immune functions.

  Effect

  Beneficial

  Effect size

  Small

• Antioxidant Status, Blood Constituents and Immune Response of Broiler Chickens Fed Two Types of Diets with or without Different Concentrations of Active Yeast.

  • 2022-02-12
  • Clinical Trial · n = 216
  • Animals : an open access journal from MDPI 12(4)
  • • Youssef A Attia
    • Hanan Al-Khalaifah
    • Hatem S Abd El-Hamid
    • Mohammed A Al-Harthi
    • Salem R Alyileili
    • Ali A El-Shafey

  • PubMed: 35203163
  • DOI: 10.3390/ani12040453

  4 Insights on

  • Improved Immune Function

  • High evidence

  improved ... the immune status ... and the immune response to Newcastle disease virus (NDV) and avian influenza (AI)

  Effect

  Beneficial

  Effect size

  Moderate

• Targeted Application of Functional Foods as Immune Fitness Boosters in the Defense against Viral Infection.

  • 2023-07-28
  • Review
  • Nutrients 15(15)
  • • Dearbhla Finnegan
    • Restituto Tocmo
    • Restituto Tocmo
    • Christine Loscher

  • PubMed: 37571308
  • DOI: 10.3390/nu15153371

  1 Insight on

  • Improved Immune Function

  • Moderate evidence
  • Rigorous Journal

  functional foods, including dairy proteins and hydrolysates, plant-based functional foods, fermentates... Our findings reveal four key immunity boosting mechanisms by functional foods

  Effect

  Beneficial

  Effect size

  Moderate

• Postbiotics: Multifunctional Microbial Products Transforming Animal Health and Performance.

  • 2025-12-12
  • Review
  • Veterinary sciences 12(12)
  • • Sahdeo Prasad
    • Bhaumik Patel
    • Prafulla Kumar
    • Rajiv Lall

  • PubMed: 41472171
  • DOI: 10.3390/vetsci12121191

  13 Insights on

  • Improved Immune Function

  • Low evidence

  They enhance antioxidant enzymes... promote the maturation and function of immune cells, and increasing secretory IgA production.

  Effect

  Beneficial

  Effect size

  Moderate

• Immunomodulatory effects and gut microbiota modulation by brewer's yeast mannatide in cyclophosphamide-induced immunosuppression mice.

  • 2026-02-02
  • Archives of microbiology 208(4)
  • • Shuang Zhao
    • Haidi Wang
    • Shuo Zhao
    • Jia Yu
    • Yuxi Wei

  • PubMed: 41627476
  • DOI: 10.1007/s00203-026-04725-9

  3 Insights on

  • Improved Immune Function

  • Low evidence
  • Animal Study

  MTE administration alleviated body weight loss, restored organ morphology, and increased immune cytokines (TNF-α and IFN-γ) in immunosuppressed mice.

  Effect

  Beneficial

  Effect size

  Moderate

• Saccharomyces cerevisiae derived postbiotic alters gut microbiome metabolism in the human distal colon resulting in immunomodulatory potential in vitro.

  • 2024-02-12
  • Frontiers in microbiology 15
  • • Cindy Duysburgh
    • Lisa Miclotte
    • Justin B Green
    • Kevin T Watts
    • Maria I Sardi
    • Anirikh Chakrabarti
    • Ehsan Khafipour
    • Massimo Marzorati

  • PubMed: 38410391
  • DOI: 10.3389/fmicb.2024.1358456

  4 Insights on

  • Improved Immune Function

  • Low evidence

  Investigation of host-microbiome interactions confirmed the immunomodulatory potential of the applied test product.

  Effect

  Beneficial

  Effect size

  Small