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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Collagen Protein and Reduced Interleukin-6 Levels

Doses used in studies

g/day: 10–25 (median 17.5, IQR 13.75–21.25) — 2 studies

Time to effect

Median: 5 days · IQR 4 days–6 days · Range 3 days–7 days — Reported in 2 of 2 studies

2 of 2 papersPopulation:

Comparing the Effects of Collagen Hydrolysate and Dairy Protein on Recovery from Eccentric Exercise: A Double Blind, Placebo-Controlled Study.
- 2024-12-20
- RCT
- Nutrients 16(24)
- - Rachel Barclay
  - Jane Coad
  - Katie Schraders
  - Matthew J Barnes
- PubMed: 39771010
- DOI: 10.3390/nu16244389
8 Insights on
- Reduced Interleukin-6 Levels
- High evidence
- Rigorous Journal
- Adults
no group or interaction effects (all p > 0.05) were observed for any of the outcome measures
Effect
Neutral
Effect size
Small
Significant
No
Dose
25 g protein immediately post-exercise and once daily for three days
The effects of collagen peptides on exercise-induced gastrointestinal stress: a randomized, controlled trial.
- 2022-11-12
- RCT · n = 20
- European journal of nutrition 62(2)
- - Guy Taylor
  - Amber Leonard
  - Jonathan C Y Tang
  - Rachel Dunn
  - William D Fraser
  - Nicolina Virgilio
  - Janne Prawitt
  - Emma Stevenson
  - Tom Clifford
- PubMed: 36370176
- DOI: 10.1007/s00394-022-03051-2
8 Insights on
- Reduced Interleukin-6 Levels
- High evidence
- Rigorous Journal
- Athletes
There were no differences in MCP-1, IL-6, and IL-8 between the CP and CON trials (all P > 0.05)
Effect
Neutral
Effect size
Small
Significant
No
Dose
10 g·day⁻¹