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Exploring NAD+ Supplement Efficacy vs. IV Therapy for Energy Enhancement

A 30-year-old explores the effectiveness of NAD+ supplements after four months of use. The conversation delves into potential reasons for lack of visible benefits and evaluates the option of switching to NAD+ IV therapy for more immediate results, emphasizing consultation with healthcare providers.

  • NAD+ supplement or IV therapy? (30F)
    I’ve been taking Nad+/NMM supplement from various brands for about 4 months. Honestly, no results or difference on energy level I could tell. Does it mean nad supplements just simple don’t work for me? Should I just go for nad IV therapy instead?

  • Nicotinamide adenine dinucleotide (NAD+) plays a crucial role in energy production, DNA repair, and other biological processes1. While oral supplements like Nicotinamide Mononucleotide (NMN) can elevate NAD+ levels with some success, their efficacy can vary based on individual factors such as absorption rates and personal metabolic responses1.

    Intravenous (IV) NAD+ therapy has been shown to provide more immediate and noticeable benefits in certain scenarios, particularly in clinical settings like substance use disorder treatment where there is significant evidence of its efficacy in attenuating symptoms such as cravings and anxiety2. However, evidence remains limited for its broad applications and more research is needed to confirm its long-term benefits and safety across different conditions2.

    If you've tried NAD+ supplements without noticeable effects, it might be worth consulting with a healthcare provider to explore whether IV therapy is suitable for you. They can assess your specific situation and health goals, considering any potential risks and benefits.

    Footnotes

    1. Nady Braidy et al., "NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis," PubMed, 2020. ↩ ↩2

    2. Kenneth Blum et al., "Nicotinamide Adenine Dinucleotide (NAD+) and Enkephalinase Inhibition infusions significantly attenuate psychiatric burden sequalae in substance use disorder," PubMed, 2021. ↩ ↩2

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