Fatigue can often be alleviated through appropriate dietary supplementation. Various nutrients have been identified to help mitigate physical and mental fatigue¹²³.

1. Coenzyme Q10 (CoQ10): This antioxidant and mitochondrial electron transport chain component has been shown in multiple studies to reduce fatigue significantly. It is effective for both healthy individuals and those with chronic illness¹.

2. Vitamin B Complex: B vitamins play a critical role in energy metabolism. Supplementing with a B complex (including B1, B2, B3, B5, B6, B8, B9, and B12) has been demonstrated to improve physical performance and reduce fatigue⁴⁵.

3. L-Carnitine: This amino acid derivative plays a central role in the production of energy by transporting fatty acids into your cells’ mitochondria. It has been shown to reduce fatigue, especially in people suffering from chronic fatigue syndrome².

4. Vitamin C and D: Both vitamins have essential roles in energy production and overall health. Vitamin C is an antioxidant that helps to reduce oxidative stress, which can cause fatigue. Vitamin D, on the other hand, plays a role in muscle function and is another critical nutrient for reducing fatigue¹.

5. Zinc and Magnesium: These minerals are essential for many biochemical processes in the body, including those related to energy production. Magnesium is specially known for its role in neuromuscular transmission and muscle contraction⁵.

6. Alpha-Lipoic Acid: This antioxidant can help to improve cellular energy production and reduce oxidative stress, which may contribute to fatigue².

If you're interested in specific product recommendations containing these supplements, please let me know, and I can search for them on Pillser.

Footnotes

1. Michael Barnish, et al. "Nutrient Therapy for the Improvement of Fatigue Symptoms," PubMed, 2023. ↩ ↩² ↩³

2. Garth L. Nicolson, "Mitochondrial Dysfunction and Chronic Disease: Treatment With Natural Supplements," NCBI, 2014. ↩ ↩² ↩³

3. Kei Mizuno, et al. "Ubiquinol-10 Intake Is Effective in Relieving Mild Fatigue in Healthy Individuals," NCBI, 2020. ↩

4. Mon-Chien Lee, et al. "A functional evaluation of anti-fatigue and exercise performance improvement following vitamin B complex supplementation in healthy humans," NCBI, 2023. ↩

5. Anne-Laure Tardy, et al. "Vitamins and Minerals for Energy, Fatigue and Cognition," NCBI, 2020. ↩ ↩²