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Maximizing Vitamin D3 Benefits: The Role of Probiotics and Key Cofactors

Explore how combining Vitamin D3 with probiotics, magnesium, and Vitamin K2 can enhance absorption and health benefits. Discover the synergy for improved gut health, hormonal balance, and bone health. Learn about essential cofactors for optimal Vitamin D activation and function.


  • what do I need to add when taking vitamin D3?

  • When taking Vitamin D3, it might be beneficial to consider combining it with probiotics. Studies suggest that this combination can enhance health benefits by improving gut health, mental health, hormonal balance, inflammatory responses, and oxidative stress parameters12. Probiotics can also increase the intestinal absorption of Vitamin D, thereby enhancing its efficacy3.

    Footnotes

    1. Myriam Abboud, "The Health Effects of Vitamin D and Probiotic Co-Supplementation: A Systematic Review of Randomized Controlled Trials," NCBI, 2020.

    2. Katarzyna Przewłócka, "Effects of Probiotics and Vitamin D3 Supplementation on Sports Performance Markers in Male Mixed Martial Arts Athletes: A Randomized Trial," NCBI, 2023.

    3. Vahidreza Ostadmohammadi, "Vitamin D and probiotic co-supplementation affects mental health, hormonal, inflammatory and oxidative stress parameters in women with polycystic ovary syndrome," NCBI, 2021.

  • How about any cofactors?

  • When taking Vitamin D3, it's beneficial to consider cofactors that assist in its absorption and function:

    1. Magnesium: This is crucial for the activation of Vitamin D. Without adequate magnesium, Vitamin D cannot be metabolized properly in the body, which may render it ineffective1.

    2. Vitamin K2: These two vitamins work synergistically to maintain bone and cardiovascular health. Vitamin K2 helps direct calcium to the bones and teeth and away from places where it shouldn't be, like the arteries2.

    Footnotes

    1. Anne Marie Uwitonze, "Role of Magnesium in Vitamin D Activation and Function," PubMed, 2018.

    2. Adriana J. van Ballegooijen, "The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review," NCBI, 2017.

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