Magnesium di-citrate is a form of magnesium supplement that has been studied for its potential benefits in managing certain health conditions, particularly migraines. Research suggests that magnesium supplementation, specifically in the form of magnesium citrate, may help reduce the frequency and severity of migraine attacks¹. In a study involving migraine patients, daily supplementation with 600 mg of magnesium citrate resulted in a significant decrease in migraine attack frequency and severity¹.

Moreover, magnesium is involved in blocking NMDA receptors, which can reduce the central sensitization that contributes to neuropathic pain and other pain conditions². It is thought that magnesium's muscle-relaxing properties and role in nerve transmission might also contribute to its effects on pain management².

It's essential to consider that while magnesium can be beneficial, it may cause side effects like diarrhea in some individuals¹. Therefore, anyone considering magnesium supplementation for migraines or other conditions should consult with a healthcare professional to ensure safety and suitability for their specific circumstances.

Footnotes

1. Lisa A. Yablon, "Magnesium in the Central Nervous System: Magnesium in headache," NCBI Bookshelf. ↩ ↩² ↩³

2. Hyo-Seok Na, "The role of magnesium in pain: Magnesium in the Central Nervous System," NCBI Bookshelf. ↩ ↩²