June 2008 Supplement Research Papers

• June 3

  • Probiotic products in Canada with clinical evidence: what can gastroenterologists recommend?

    • 2008-06-03
    • Review
    • Canadian journal of gastroenterology = Journal canadien de gastroenterologie 22(2)
    • • G Reid
      • K Anukam
      • T Koyama

    • PubMed: 18299736
    • DOI: 10.1155/2008/843892

    1 Insight on

    • Improved Gastrointestinal Health

    • Low evidence
• June 17

  • Preliminary investigations of the colonisation of upper respiratory tract tissues of infants using a paediatric formulation of the oral probiotic Streptococcus salivarius K12

    • 2008-06-17
    • Clinical Trial · n = 19
    • European Journal of Clinical Microbiology & Infectious Diseases 27(12)
    • • Dan Power
      • Jeremy P. Burton
      • C. Chilcott
      • Patrick J. D. Dawes
      • J. Tagg

    • PubMed: 18560907
    • DOI: 10.1007/s10096-008-0569-4

    3 Insights on

    • Increased Salivary Streptococcus salivarius K12 Levels
    • Colonization of Nasopharynx or Adenoid Tissue
    • Colonisation of Nasopharynx or Adenoid Tissue with S. salivarius K12

    • High evidence
    • Highly Cited
• June 19

  • Oral administration of heat-killed Lactobacillus brevis SBC8803 ameliorates the development of dermatitis and inhibits immunoglobulin E production in atopic dermatitis model NC/Nga mice.

    • 2008-06-19
    • Clinical Trial · n = 20
    • Biological and Pharmaceutical Bulletin 31(5)
    • • S. Segawa
      • Atsushi Hayashi
      • Y. Nakakita
      • H. Kaneda
      • J. Watari
      • H. Yasui

    • PubMed: 18451512
    • DOI: 10.1248/BPB.31.884

    3 Insights on

    • Reduced Incidence of Dermatitis
    • Reduced IgE Production
    • Increased Immunosuppressive Cytokine Production

    • Low evidence
    • Animal Study
• Undated – 1 supplement study

  • Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells by modulating dendritic cell function.

    • 2008-06
    • Immunobiology 213(5)
    • • H. Kanzato
      • S. Fujiwara
      • W. Ise
      • S. Kaminogawa
      • R. Sato
      • S. Hachimura

    • PubMed: 18472048
    • DOI: 10.1016/j.imbio.2007.10.001

    7 Insights on

    • Reduced T Cell Responsiveness
    • Reduced Proliferation of CD4(+) T Cells
    • Increased Apoptosis in T Cells
    • Increased IFN-gamma Secretion from Naïve T Cells
    • Reduced IL-4 Secretion from Naïve T Cells
    • Modulated Dendritic Cell Function
    • Increased Apoptosis of OVA-specific TCR Tg T Cells

    • Low evidence