Dietary Saccharomyces cerevisiae improves intestinal flora structure and barrier function of Pekin ducks.

2023-01
Poultry science 102(1)

PubMed: 36436368
DOI: 10.1016/j.psj.2022.101940

Study Design

Type: Randomized Controlled Trial (RCT)
Sample size: n = 180
Population: 180 1-day-old Pekin ducks
Methods: randomly divided into 3 groups with 6 replicates in each group and 10 birds per replicate; control group fed the basal diet, experimental groups fed basal diets supplemented with 600 mg/kg SC (LSC) and 1,200 mg/kg (HSC); trial lasted for 42 d

Animal Study

This study aimed at investigating the effects of dietary Saccharomyces cerevisiae (SC) on the intestinal flora structure and barrier function of Pekin duck. A total of 180 1-day-old Pekin ducks were randomly divided into 3 groups with 6 replicates in each group and 10 birds per replicate. The birds in the control group (CON) were fed the basal diet, and those in the experimental group were fed the basal diets supplemented with 600 mg/kg SC (LSC) and 1,200 mg/kg (HSC), respectively. The trial lasted for 42 d. Results showed that LSC and HSC treatments tended to improve the feed conversion efficiency during the trial. The ileum length of birds in the LSC and HSC groups was elevated. Additionally, with 600mg/kg SC supplemented, the mRNA levels of villin, claudin3, and MUC 2 in d21 were up-regulated, as well as the mRNA levels of villin, claudin3, occludin, i-FABP, ZO-1, and MUC 2 in d42. In addition, dietary SC supplementation improved the α-diversity of the bacteria in cecal chyme and tended to increase the abundance (RA) of Bacteroidetes (P = 0.071). Besides, the RA of Ruminococcaceae_UCG-014 was raised in the LSC group. Beyond that, the RA of Proteobacteria was descended with two levels of SC added. In conclusion, dietary Saccharomyces cerevisiae, particularly at 600 mg/kg level, improved the intestinal flora structure and barrier function of Pekin duck.

Research Insights

Supplement	Dose	Health Outcome	Effect Type	Effect Size	Source
Saccharomyces cerevisiae	—	Improved Gut Microbiota Composition	Beneficial	Moderate	View source dietary SC supplementation improved the α-diversity of the bacteria in cecal chyme and tended to increase the abundance (RA) of Bacteroidetes... the RA of Ruminococcaceae_UCG-014 was raised in the LSC group. Beyond that, the RA of Proteobacteria was descended with two levels of SC added.
Saccharomyces cerevisiae	—	Improved Intestinal Barrier Function	Beneficial	Moderate	View source 600 mg/kg SC supplemented, the mRNA levels of villin, claudin3, and MUC 2 in d21 were up-regulated, as well as the mRNA levels of villin, claudin3, occludin, i-FABP, ZO-1, and MUC 2 in d42.
Saccharomyces cerevisiae	—	Increased Ileum Length	Beneficial	Small	View source The ileum length of birds in the LSC and HSC groups was elevated