Effects of a Singular Dose of Mangiferin-Quercetin Supplementation on Basketball Performance: A Double-Blind Crossover Study of High-Level Male Players.

2024-01-04
Nutrients 16(1)
- Dimitrios I Bourdas
- Antonios K Travlos
- Athanasios Souglis
- Georgia Stavropoulou
- Emmanouil Zacharakis
- Dimitrios C Gofas
- Panteleimon Bakirtzoglou

PubMed: 38201999
DOI: 10.3390/nu16010170

Study Design

Type: Randomized Controlled Trial (RCT)
Population: 38 high-level male basketball players
Methods: Double-blind, cross-over design; mangiferin-quercetin (84 mg/140 mg) or placebo given one hour before a basketball exercise simulation test (BEST)
Blinding: Double-blind
Duration: 2 weeks
Funding: Unclear

Rigorous Journal

Pre-exercise mangiferin-quercetin may enhance athletic performance. This study investigated the effect of mangiferin-quercetin supplementation on high-level male basketball players during a basketball exercise simulation test (BEST) comprising 24 circuits of 30 s activities with various movement distances. The participants were divided into two groups (EXP = 19 and CON = 19) and given a placebo one hour before the BEST (PRE-condition). The following week, the EXP group received mangiferin-quercetin (84 mg/140 mg), while the CON group received a placebo (POST-condition) before the BEST in a double-blind, cross-over design. The mean heart rate (HR) and circuit and sprint times (CT and ST) during the BEST were measured, along with the capillary blood lactate levels (La^-), the subjective rating of muscle soreness (RPMS), and the perceived exertion (RPE) during a resting state prior to and following the BEST. The results showed significant interactions for the mean CT (p = 0.013) and RPE (p = 0.004); a marginal interaction for La^- (p = 0.054); and non-significant interactions for the mean HR, mean ST, and RPMS. Moreover, the EXP group had significantly lower values in the POST condition for the mean CT (18.17 ± 2.08 s) and RPE (12.42 ± 1.02) compared to the PRE condition (20.33 ± 1.96 s and 13.47 ± 1.22, respectively) and the POST condition of the CON group (20.31 ± 2.10 s and 13.32 ± 1.16, respectively) (p < 0.05). These findings highlight the potential of pre-game mangiferin-quercetin supplementation to enhance intermittent high-intensity efforts in sports such as basketball.

Research Insights

Quercetin→Improved Exercise Performance
The results showed significant interactions for the mean CT (p = 0.013) ... Moreover, the EXP group had significantly lower values in the POST condition for the mean CT (18.17 ± 2.08 s) compared to the PRE condition (20.33 ± 1.96 s) and the POST condition of the CON group (20.31 ± 2.10 s) (p < 0.05).
Effect
Beneficial
Effect size
Moderate
Dose
140 mg
Quercetin→Improved Sprint Time
The results showed ... non-significant interactions for the mean HR, mean ST, and RPMS.
Effect
Neutral
Effect size
Small
Dose
140 mg
Quercetin→Reduced Heart Rate
The results showed ... non-significant interactions for the mean HR, mean ST, and RPMS.
Effect
Neutral
Effect size
Small
Dose
140 mg
Quercetin→Reduced Lactate Levels
The results showed ... a marginal interaction for La- (p = 0.054).
Effect
Neutral
Effect size
Small
Dose
140 mg
Quercetin→Reduced Muscle Soreness
The results showed ... non-significant interactions for the mean HR, mean ST, and RPMS.
Effect
Neutral
Effect size
Small
Dose
140 mg
Quercetin→Reduced Perceived Exertion
The results showed significant interactions for ... RPE (p = 0.004) ... Moreover, the EXP group had significantly lower values in the POST condition for ... RPE (12.42 ± 1.02) compared to the PRE condition (13.47 ± 1.22) and the POST condition of the CON group (13.32 ± 1.16) (p < 0.05).
Effect
Beneficial
Effect size
Small
Dose
140 mg
Salacia→Improved Exercise Performance
The results showed significant interactions for the mean CT (p = 0.013) ... Moreover, the EXP group had significantly lower values in the POST condition for the mean CT (18.17 ± 2.08 s) compared to the PRE condition (20.33 ± 1.96 s) and the POST condition of the CON group (20.31 ± 2.10 s) (p < 0.05).
Effect
Beneficial
Effect size
Moderate
Dose
140 mg
Salacia→Improved Sprint Time
The results showed ... non-significant interactions for the mean HR, mean ST, and RPMS.
Effect
Neutral
Effect size
Small
Dose
140 mg
Salacia→Reduced Heart Rate
The results showed ... non-significant interactions for the mean HR, mean ST, and RPMS.
Effect
Neutral
Effect size
Small
Dose
140 mg
Salacia→Reduced Lactate Levels
The results showed ... a marginal interaction for La- (p = 0.054).
Effect
Neutral
Effect size
Small
Dose
140 mg
Salacia→Reduced Muscle Soreness
The results showed ... non-significant interactions for the mean HR, mean ST, and RPMS.
Effect
Neutral
Effect size
Small
Dose
140 mg
Salacia→Reduced Perceived Exertion
The results showed significant interactions for ... RPE (p = 0.004) ... Moreover, the EXP group had significantly lower values in the POST condition for ... RPE (12.42 ± 1.02) compared to the PRE condition (13.47 ± 1.22) and the POST condition of the CON group (13.32 ± 1.16) (p < 0.05).
Effect
Beneficial
Effect size
Small
Dose
140 mg