Effects of Ganoderma lucidum and Ceratonia siliqua on blood glucose, lipid profile, and body composition in women with fibromyalgia.

2021-02-01
Nutricion hospitalaria 38(1)
- Francesco Pazzi
- José Carmelo Adsuar
- Francisco Javier Domínguez-Muñoz
- Miguel Ángel García-Gordillo
- Narci Gusi
- Daniel Collado-Mateo

PubMed: 33319566
DOI: 10.20960/nh.03190

Study Design

Type: Randomized Controlled Trial (RCT)
Population: women with fibromyalgia
Methods: double-blind randomized pilot trial, 6 g/day of micro-milled carpophore powder of Ganoderma lucidum or Ceratonia siliqua flour for 6 weeks
Blinding: Double-blind
Duration: 6 weeks
Funding: Unclear

Introduction

Introduction: fibromyalgia (FM) is a chronic rheumatic disorder that is related to high levels of cholesterol, high values of diastolic pressure, higher waist-to-hip-ratio (WHR), and higher body mass index. Objectives: the aim of this study was to evaluate the effects of Ganoderma lucidum (GL) and Ceratonia siliqua (CS) on blood parameters and anthropometrical measures in women with fibromyalgia. Methods: a double-blind randomized pilot trial was carried out. One group took 6 g/day of micro-milled carpophore powder of GL for 6 weeks, while the second group took the same dose of CS flour. Fasting glucose, cholesterol, triglycerides levels, weight, fat mass, muscular mass, waist-hip ratio, and blood pressure were assessed. Results: our results did not show any statistically significant differences in any of the outcome measures, even if there was a CS tendency to reduce fasting glucose levels and increase WHR. Conclusions: our results did not support the utility of both GL and CS as nutritional supplements to control blood parameters and anthropometric measures as assessed in women with fibromyalgia. Due to the limitations of the research, additional studies will be necessary to confirm our findings.

Research Insights

Carob→Increased Muscle Mass
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Carob→Reduced Blood Cholesterol
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Carob→Reduced Blood Pressure
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Carob→Reduced Body Fat Mass
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Carob→Reduced Body Weight
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Carob→Reduced Fasting Blood Glucose Levels
even if there was a CS tendency to reduce fasting glucose levels and increase WHR
Effect
Neutral
Effect size
Small
Dose
6 g/day
Carob→Reduced Triglyceride Levels
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Carob→Reduced Waist-to-Height Ratio
even if there was a CS tendency to reduce fasting glucose levels and increase WHR
Effect
Neutral
Effect size
Small
Dose
6 g/day
Reishi→Increased Muscle Mass
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Reishi→Reduced Blood Cholesterol
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Reishi→Reduced Blood Pressure
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Reishi→Reduced Body Fat Mass
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Reishi→Reduced Body Weight
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Reishi→Reduced Fasting Blood Glucose Levels
even if there was a CS tendency to reduce fasting glucose levels and increase WHR
Effect
Neutral
Effect size
Small
Dose
6 g/day
Reishi→Reduced Triglyceride Levels
our results did not show any statistically significant differences in any of the outcome measures
Effect
Neutral
Effect size
Small
Dose
6 g/day
Reishi→Reduced Waist-to-Height Ratio
even if there was a CS tendency to reduce fasting glucose levels and increase WHR
Effect
Neutral
Effect size
Small
Dose
6 g/day