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Evidence-Based Supplement Research
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Reishi and Reduced Triglyceride Levels

Research synthesisVery low evidenceSmall effect3 studies · 1 beneficial · 2 neutral · 0 harmful

Across 3 studies, 1 reported a small beneficial effect of Reishi (Ganoderma lucidum spore oil) on reducing triglyceride levels, while 2 found neutral results. The beneficial effect was observed in a randomized controlled trial with 110 dyslipidemic participants over 12 weeks, using a spore oil form. The median study duration was 63 days, and effect sizes across all studies were consistently small. The evidence base is very small (only 3 studies), so conclusions are preliminary.

  • Studied populations: People with dyslipidemia

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. The one beneficial study used a spore oil form, while the neutral studies did not specify form; differences in formulation may affect outcomes.

Generated Jun 10, 2026
Doses used in studies
  • g/day: 6 (median 6, IQR 6–6) — 1 study
  • mg/day: 200–11,200 (median 5,700, IQR 200–11,200) — 1 study
Time to effect
Median: 9 weeks · IQR 7.5 weeks–10.5 weeks · Range 6 weeks–2.8 months — Reported in 2 of 3 studies
Safety in these studies
3 of 3 papers
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