Exploring the efficacy of a novel prebiotic-like growth promoter on broiler chicken production performance.
- 2024-03
- Veterinary and animal science 23
- Zulfqarul Haq
- Ankur Rastogi
- Ramesh Kumar Sharma
- Pratiksha Raghuwanshi
- Maninder Singh
- Azmat Alam Khan
- Syed Mudasir Ahmad
- PubMed: 38283334
- DOI: 10.1016/j.vas.2023.100331
This study attempts to isolate a candidate growth promoter from the ovine paunch waste and scrutinize its effects on the production performance of broiler chickens as compared to mannan-oligosaccharide (MOS), a prebiotic, and lincomycin, an antibiotic growth promoter (AB). The paunch waste collected from slaughtered sheep was processed to remove particulate matter. The clarified liquid was then added to an excess of ethanol (1:9 ratio), and the resultant precipitate {(novel growth-promoting paunch extract (NGPE)} was collected, dried, and stored. In vitro increase in cell density for probiotic bacteria viz. Lactobacillus rhamnosus and Enterococcus faecalis (Log10 CFU/ml) were significantly higher (P < 0.01) in NGPE supplemented media (2.78 ± 0.11 and 2.77 ± 0.10) as compared to that on MOS (1.28 ± 0.05 and 2.49 ± 0.09) and glucose (1.09 ± 0.04 and 1.12 ± 0.04) supplemented media. In the in-vivo trial of six weeks duration with broiler chickens (Cobb-400), NGPE supplementation resulted in significantly higher growth in weeks IV (P < 0.05) and VI (P < 0.01) of age in comparison to MOS and AGP supplemented groups, a lower (P < 0.01) cumulative feed conversion ratio in comparison to MOS supplemented groups, and a higher (P < 0.01) cumulative protein efficiency ratio compared to MOS and AGP supplementation. NGPE supplementation also lowered lipid peroxidation (P < 0.01), increased reduced glutathione activity (P < 0.01) in chicken erythrocytes, and boosted the lactic acid bacteria count in the cecal contents (P < 0.01). This is the first report of the isolation of a paunch waste extract that increased the in vitro growth of probiotic bacteria and improved the production performance of broiler chickens.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Lactobacillus rhamnosus lysate powder | Enhanced Protein Efficiency Ratio | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Improved Feed Conversion Ratio | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Improved Growth Performance in Chickens | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Improved Growth of Beneficial Bacteria | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Improved Production Performance | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Increased Antioxidant Activity | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Increased Bifidobacterial Growth | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Increased Cecal Lactic Acid Bacteria | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Reduced Lipid Peroxidation | Beneficial | Moderate |
| Lactobacillus rhamnosus lysate powder | Reduced Oxidative Stress | Beneficial | Moderate |