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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Lactobacillus rhamnosus and Increased Antioxidant Activity

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects on antioxidant activity, with effect sizes predominantly moderate. However, only one study reached statistical significance, and the evidence is drawn from non-human populations (broiler chickens and in vitro), limiting applicability to humans. No consistent dose or form was identified.

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. Additionally, all studies are in non-human models (broiler chickens, in vitro isolates) with no human trials, so relevance to human supplementation is uncertain.

Generated May 12, 2026
3 of 3 papers
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