Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats.

1998-06
International Journal of Food Microbiology 42(1-2)
- M. Johansson
- S. Nobaek
- A. Berggren
- M. Nyman
- I. Björck
- S. Ahrné
- Bengt Jeppsson
- G. Molin

PubMed: 9706795
DOI: 10.1016/S0168-1605(98)00055-5

Abstract

In a controlled and randomised double-blind study, 26 healthy adult volunteers consumed, for 21 d, 400 ml of a rose-hip drink containing oats (0.7 g/100ml) fermented with Lactobacillus plantarum DSM 9843 (RHL; containing 5 x 10(7) cfu ml(-1)), and 22 volunteers in a second group the same amount of a pure rose-hip drink (RH). Significant increases in the total faecal concentration of carboxylic acids (P < 0.05 after 1 week and P < 0.01 after 3 weeks of intake), acetic acid (P < 0.01 after 3 weeks of intake) and propionic acid (P < 0.01 after 3 weeks of intake and P < 0.05 eight days after intake ceased) were recorded in the RHL group, indicating increased fermentation in the colon. In both groups a significant increase was obtained in the concentration of faecal lactic acid (P < 0.001 after 1 and 3 weeks of intake). No changes were seen in the concentration of faecal butyrate. The numbers of faecal bifidobacteria and lactobacilli increased significantly in both groups after 3 weeks of intake. Sulphite-reducing clostridia rapidly decreased in the group receiving the product with Lb. plantarum DSM 9843 after 1 week of intake, and then also in the pure rose-hip group after 3 weeks of intake. No changes were seen in the numbers of total anaerobes, gram-negative anaerobes or total aerobes during administration. Lb. plantarum DSM 9843 was recovered in faeces from all volunteers in the RHL group. Median amounts were 7.0 (5.0-8.8) log10 cfu g(-1) after one week of intake, and 6.7 (5.0-8.9) log10 cfu g(-1) after 3 weeks, respectively. The strain was still recovered from faeces of five volunteers 8 d after administration ceased (> 4.8 log10 cfu g(-1)). During the period of intake the volunteers in the RHL group experienced a significant increase in stool volume, a significant decrease in flatulence and slightly softer stools. Volunteers in the RH group experienced a slight but significant decrease in stool volume.

Research Insights

Supplement	Health Outcome	Effect Type	Effect Size
Bifidobacterium plantarum	Improved Stool Softness	Beneficial	Small
Bifidobacterium plantarum	Increased Colonic Fermentation	Beneficial	Moderate
Lactobacillus helveticus Rosell-52	Improved Stool Softness	Beneficial	Small
Lactobacillus helveticus Rosell-52	Increased Colonic Fermentation	Beneficial	Moderate
Lactobacillus helveticus Rosell-52	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus helveticus Rosell-52	Increased Stool Volume	Beneficial	Moderate
Lactobacillus helveticus Rosell-52	Reduced Flatulence	Beneficial	Small
Lactobacillus helveticus Rosell-52	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus helveticus Rosell-52 ME	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus helveticus Rosell-52 ME	Increased Stool Volume	Beneficial	Moderate
Lactobacillus helveticus Rosell-52 ME	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus helveticus Rosell-52 ME	Reduced Flatulence	Beneficial	Small
Lactobacillus helveticus Rosell-52 ME	Reduced Stool Volume	Harmful	Small
Lactobacillus helveticus Rosell-52 ME	Reduced Straining	Beneficial	Small
Lactobacillus helveticus Rosell-52 ME	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus helveticus Rosell-52ND	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus helveticus Rosell-52ND	Increased Stool Volume	Beneficial	Moderate
Lactobacillus helveticus Rosell-52ND	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus helveticus Rosell-52ND	Reduced Flatulence	Beneficial	Small
Lactobacillus helveticus Rosell-52ND	Reduced Straining	Beneficial	Small
Lactobacillus helveticus Rosell-52ND	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus LB	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus LB	Increased Stool Volume	Beneficial	Moderate
Lactobacillus LB	Reduced Flatulence	Beneficial	Small
Lactobacillus LB	Reduced Straining	Beneficial	Small
Lactobacillus LB	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum	Increased Faecal Carboxylic Acid Concentration	Beneficial	Moderate
Lactobacillus plantarum	Increased Fecal Acetic Acid Concentration	Beneficial	Large
Lactobacillus plantarum	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum	Increased Fecal Propionic Acid Levels	Beneficial	Moderate
Lactobacillus plantarum	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum	No Change in Faecal Butyrate Concentration	Neutral	Small
Lactobacillus plantarum	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum	Reduced Stool Volume	Harmful	Small
Lactobacillus plantarum	Reduced Straining	Beneficial	Small
Lactobacillus plantarum	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum	Unchanged Total Anaerobes, Gram-negative Anaerobes, and Total Aerobes	Neutral	Small
Lactobacillus plantarum 14D	Improved Stool Softness	Beneficial	Small
Lactobacillus plantarum 14D	Increased Fecal Acetic Acid Concentration	Beneficial	Large
Lactobacillus plantarum 14D	Increased Fecal Concentration of Propionic Acid	Beneficial	Large
Lactobacillus plantarum 14D	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum 14D	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum 14D	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum 14D	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum 14D	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum DR7	Improved Stool Softness	Beneficial	Small
Lactobacillus plantarum DR7	Increased Fecal Acetic Acid Concentration	Beneficial	Large
Lactobacillus plantarum DR7	Increased Fecal Concentration of Propionic Acid	Beneficial	Large
Lactobacillus plantarum DR7	Increased Fecal Lactic Acid Concentration	Beneficial	Large
Lactobacillus plantarum DR7	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum DR7	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum DR7	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum DR7	Reduced Stool Volume	Harmful	Small
Lactobacillus plantarum DR7	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum DSM 6595	Improved Stool Softness	Beneficial	Small
Lactobacillus plantarum DSM 6595	Increased Fecal Acetic Acid Concentration	Beneficial	Large
Lactobacillus plantarum DSM 6595	Increased Fecal Concentration of Propionic Acid	Beneficial	Large
Lactobacillus plantarum DSM 6595	Increased Fecal Lactic Acid Concentration	Beneficial	Large
Lactobacillus plantarum DSM 6595	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum DSM 6595	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum DSM 6595	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum DSM 6595	Reduced Stool Volume	Harmful	Small
Lactobacillus plantarum DSM 6595	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum DSM 6596	Improved Stool Softness	Beneficial	Small
Lactobacillus plantarum DSM 6596	Increased Fecal Acetic Acid Concentration	Beneficial	Large
Lactobacillus plantarum DSM 6596	Increased Fecal Concentration of Propionic Acid	Beneficial	Large
Lactobacillus plantarum DSM 6596	Increased Fecal Lactic Acid Concentration	Beneficial	Large
Lactobacillus plantarum DSM 6596	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum DSM 6596	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum DSM 6596	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum DSM 6596	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum HA-119	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum HA-119	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum HA-119	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum KABP™-061	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum KABP™-061	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum KABP™-061	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum KABP™-061	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum KABP™-061	Reduced Straining	Beneficial	Small
Lactobacillus plantarum KABP™-061	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum N13	Increased Fecal Short-Chain Fatty Acids	Beneficial	Moderate
Lactobacillus plantarum R1012	Increased Colonic Fermentation	Beneficial	Moderate
Lactobacillus plantarum R1012	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum R1012	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum R1012	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum R1012	Reduced Straining	Beneficial	Small
Lactobacillus plantarum R1012	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum Rosell-1012	Increased Fecal Carboxylic Acids Concentration	Beneficial	Moderate
Lactobacillus plantarum Rosell-1012	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum Rosell-1012	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum Rosell-A	Improved Stool Softness	Beneficial	Small
Lactobacillus plantarum Rosell-A	Increased Fecal Acetic Acid Concentration	Beneficial	Large
Lactobacillus plantarum Rosell-A	Increased Fecal Concentration of Propionic Acid	Beneficial	Large
Lactobacillus plantarum Rosell-A	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum Rosell-A	Increased Fecal Short-Chain Fatty Acid Levels	Beneficial	Moderate
Lactobacillus plantarum Rosell-A	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum Rosell-A	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum Rosell-A	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum SD-5209	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum SD-5209	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum SD-5209	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum SD-5209	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum SD5209	Increased Acetic Acid Levels in Feces	Beneficial	Moderate
Lactobacillus plantarum SD5209	Increased Fecal Propionic Acid Levels	Beneficial	Moderate
Lactobacillus plantarum UALp-05	Increased Fecal Lactic Acid Concentration	Beneficial	Large
Lactobacillus plantarum UALp-05	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum UALp-05	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum UALp-05	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum UALp-05	Reduced Straining	Beneficial	Small
Lactobacillus plantarum UALp-05	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum UALp-05M	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum UALp-05M	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum UALp-05M	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum UALp-05M	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum UALp-05M	Reduced Straining	Beneficial	Small
Lactobacillus plantarum UALp-05M	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate
Lactobacillus plantarum VPro 10	Increased Acetic Acid Levels in Feces	Beneficial	Moderate
Lactobacillus plantarum VPro 10	Increased Fecal Lactic Acid	Beneficial	Moderate
Lactobacillus plantarum VPro 10	Increased Fecal Propionic Acid Levels	Beneficial	Moderate
Lactobacillus plantarum VPro 10	Increased Stool Volume	Beneficial	Moderate
Lactobacillus plantarum VPro 10	Increased Total Fecal Carboxylic Acids	Beneficial	Large
Lactobacillus plantarum VPro 10	Reduced Flatulence	Beneficial	Small
Lactobacillus plantarum VPro 10	Reduced Sulphite-Reducing Clostridia	Beneficial	Moderate