The Gut Microbiome as a Major Regulator of the Gut-Skin Axis.
- 2018-07-10
- Frontiers in microbiology 9
- Iman Salem
- Amy Ramser
- Nancy Isham
- Mahmoud A Ghannoum
- PubMed: 30042740
- DOI: 10.3389/fmicb.2018.01459
Study Design
- Type
- Review
- Methods
- In the current review, we describe the neoteric advancement in our comprehension of how the gut microbiota communicates with the skin as one of the main regulators in the gut-skin axis. We attempted to explore how this potential link affects skin differentiation and keratinization, its influence on modulating the cutaneous immune response in various diseases, and finally how to take advantage of this communication in the control of different skin conditions.
- Highly Cited
The adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower gut maintaining a symbiosis with the human habitat. In the current review, we describe the neoteric advancement in our comprehension of how the gut microbiota communicates with the skin as one of the main regulators in the gut-skin axis. We attempted to explore how this potential link affects skin differentiation and keratinization, its influence on modulating the cutaneous immune response in various diseases, and finally how to take advantage of this communication in the control of different skin conditions.
Research Insights
consuming Lactobacillus brevis SBC8803 was associated with improved skin barrier function in healthy adult humans
- Effect
- Beneficial
- Effect size
- Small
consuming Lactobacillus brevis SBC8803 was associated with improved skin hydration in healthy adults
- Effect
- Beneficial
- Effect size
- Small