Vitamin C and Reduced Pain Intensity

• Effects of Multiple Intravenous Doses of Perioperative Vitamin C on Pain Management Following Total Hip Arthroplasty.

  • 2025-04-09
  • RCT
  • Drug design, development and therapy 19
  • • Guangtao Han
    • Yuna Ye
    • Pengde Kang

  • PubMed: 40231193
  • DOI: 10.2147/dddt.s506262

  4 Insights on

  • Reduced Pain Intensity

  • High evidence
  • Clinical

  During the perioperative term, the vitamin C group experienced ... lower VAS pain levels at rest and during exercise.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  3g of vitamin C intravenously every day during the perioperative period

• Vitamin C as an Adjuvant Analgesic Therapy in Postoperative Pain Management.

  • 2025-06-05
  • Review · n = 14
  • Journal of clinical medicine 14(11)
  • • Wioletta Mędrzycka-Dąbrowska
    • Sandra Lange
    • Sebastian Dąbrowski
    • Klaudia Długoborska
    • Renata Piotrkowska

  • PubMed: 40507754
  • DOI: 10.3390/jcm14113994

  2 Insights on

  • Reduced Pain Intensity

  • Low evidence
  • Clinical

  In all studies, regardless of the measurement time, a reduction in the pain intensity was demonstrated compared to control or placebo groups.

  Effect

  Beneficial

  Effect size

  Moderate

  Dose

  1 g to 3 g or 50 mg/kg intravenously