green tea and Reduced Low-Density Lipoprotein Level

Research synthesisModerate evidenceModerate effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies, all reported statistically significant beneficial effects on reducing LDL cholesterol, with predominantly moderate effect sizes. The evidence is drawn from systematic reviews and meta-analyses covering diverse clinical populations (e.g., MASLD, overweight/obesity, dyslipidaemia). Effects were typically observed over 90 days in the one study reporting duration.

Studied populations: Adults with metabolic dysfunction (MASLD, overweight/obesity, dyslipidaemia) or at high cardiovascular risk

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Additionally, the evidence base is small (only 4 studies) and lacks consistent reporting of dose, form, and duration, limiting practical guidance.

Generated Jul 18, 2026

Time to effect

Median: 3 months · IQR 3 months–3 months · Range 3 months–3 months — Reported in 1 of 4 studies

Safety in these studies

Overall tolerabilityReported
The included studies showed substantial heterogeneity in reported outcomes, which primarily focused on hepatic health, body weight, adverse events, glycemic control, blood lipids, and body composition.
from: Evaluating Bioactive-Substance-Based Interventions for Adults with MASLD: Results from a S
appendicitisReported
Adverse events were measured in five trials and included a diagnosis of prostate cancer, hospitalisation for influenza, appendicitis and retinal detachment but these are unlikely to be directly attributable to the intervention.
from: Green and black tea for the primary prevention of cardiovascular disease.
hospitalisation for influenzaReportedSerious adverse event
Adverse events were measured in five trials and included a diagnosis of prostate cancer, hospitalisation for influenza, appendicitis and retinal detachment but these are unlikely to be directly attributable to the intervention.
from: Green and black tea for the primary prevention of cardiovascular disease.
prostate cancerReported
Adverse events were measured in five trials and included a diagnosis of prostate cancer, hospitalisation for influenza, appendicitis and retinal detachment but these are unlikely to be directly attributable to the intervention.
from: Green and black tea for the primary prevention of cardiovascular disease.
retinal detachmentReported
Adverse events were measured in five trials and included a diagnosis of prostate cancer, hospitalisation for influenza, appendicitis and retinal detachment but these are unlikely to be directly attributable to the intervention.
from: Green and black tea for the primary prevention of cardiovascular disease.

4 of 4 papersPopulation:

Evaluating Bioactive-Substance-Based Interventions for Adults with MASLD: Results from a Systematic Scoping Review.
- 2025-01-26
- Systematic Review · n = 4,572
- Nutrients 17(3)
- - Deepa Handu
  - Kim Stote
  - Tami Piemonte
- PubMed: 39940310
- DOI: 10.3390/nu17030453
6 Insights on
- Reduced Low-Density Lipoprotein Level
- High evidence
- Rigorous Journal
- Clinical
The included studies showed substantial heterogeneity in reported outcomes, which primarily focused on hepatic health, body weight, adverse events, glycemic control, blood lipids, and body composition.
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Effects of green tea on lipid profile in overweight and obese women.
- 2024-06
- Meta-Analysis · n = 1,818
- International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 94(3-4)
- - Aixin Li
  - Qian Wang
  - Peng Li
  - Na Zhao
  - Zhaoguang Liang
- PubMed: 37082776
- DOI: 10.1024/0300-9831/a000783
4 Insights on
- Reduced Low-Density Lipoprotein Level
- High evidence
- Clinical
reduction in low-density lipoprotein cholesterol (LDL-C) (WMD: -4.49 mg/dl, 95% CI: -7.50 to -1.47, P=0.003)
Effect
Beneficial
Effect size
Small
Significant
Yes
Green and black tea for the primary prevention of cardiovascular disease.
- 2013-06-18
- Meta-Analysis · n = 821
- The Cochrane database of systematic reviews 2013(6)
- - Louise Hartley
  - Nadine Flowers
  - Jennifer Holmes
  - Aileen Clarke
  - Saverio Stranges
  - Lee Hooper
  - Karen Rees
- PubMed: 23780706
- DOI: 10.1002/14651858.cd009934.pub2
4 Insights on
- Reduced Low-Density Lipoprotein Level
- High evidence
- Mixed
LDL cholesterol (MD -0.64 mmol/L, 95% CI -0.77 to -0.52)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
not stated (varied by trial)
Nutraceuticals in the Management of Dyslipidemia: Which, When, and for Whom? Could Nutraceuticals Help Low-Risk Individuals with Non-optimal Lipid Levels?
- 2021-08-04
- Review
- Current atherosclerosis reports 23(10)
- - Arrigo F G Cicero
  - Federica Fogacci
  - Anca Pantea Stoian
  - Michal Vrablik
  - Khalid Al Rasadi
  - Maciej Banach
  - Peter P Toth
  - Manfredi Rizzo
- PubMed: 34345932
- DOI: 10.1007/s11883-021-00955-y
1 Insight on
- Reduced Low-Density Lipoprotein Level
- Low evidence
- Clinical
A growing number of meta-analyses of randomized clinical trials supports the effectiveness and tolerability of some lipid-lowering nutraceuticals such as ... green tea
Effect
Beneficial
Effect size
Moderate
Significant
Yes

green tea and Reduced Low-Density Lipoprotein Level

Evaluating Bioactive-Substance-Based Interventions for Adults with MASLD: Results from a Systematic Scoping Review.

Effects of green tea on lipid profile in overweight and obese women.

Green and black tea for the primary prevention of cardiovascular disease.

Nutraceuticals in the Management of Dyslipidemia: Which, When, and for Whom? Could Nutraceuticals Help Low-Risk Individuals with Non-optimal Lipid Levels?