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Evidence-Based Supplement Research
Evidence-Based Supplement Research

rice bran and Reduced LDL Cholesterol

Research synthesisHigh evidenceModerate effect5 studies · 5 beneficial · 0 neutral · 0 harmful

Across 5 studies, all 5 reported beneficial effects of rice bran on reducing LDL cholesterol, with a moderate effect size predominant. The evidence includes two meta-analyses and a systematic review showing statistically significant reductions (e.g., WMD: -14.580 mg/dL; p < 0.0001, and WMD: -15.11 mg/dL; 95% CI: -24.56, -5.66). Effects are typically observed at 8 weeks, with a median study duration of 56 days, and most studies involved populations with metabolic syndrome or related cardiometabolic risk factors.

  • Effective dose range: ≥30 g/day
  • Studied populations: adults with metabolic syndrome, overweight/obese adults with cardiometabolic risk factors

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Most studies focused on rice bran oil rather than whole rice bran, and effects may vary by form. The evidence base is small (only 5 studies), though consistent.

Generated Jun 12, 2026
Doses used in studies
  • g/day: 30 (median 30, IQR 3030) 1 study
  • g/mL: 30 (median 30, IQR 3030) 1 study
Time to effect
Median: 8 weeks · IQR 8 weeks8 weeks · Range 8 weeks8 weeks — Reported in 1 of 5 studies
5 of 5 papers
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