saccharomyces boulardii and Reduced Diarrhea

• Saccharomyces boulardii prevents diarrhea in critically ill tube-fed patients

  • 1997-05-26
  • RCT · n = 128
  • Intensive Care Medicine 23(5)
  • • G. Bleichner
    • H. Bléhaut
    • H. Mentec
    • D. Moyse

  • PubMed: 9201523
  • DOI: 10.1007/s001340050367

  2 Insights on

  • Reduced Diarrhea

  • High evidence
  • Highly Cited

  After adjustment for these factors, the preventive effect of S. boulardii on diarrhea was even more significant (OR = 0.61, 95% CI = 0.44-0.84, P < 0.0023).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  500 mg four times a day

• Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii: a prospective study.

  • 1989-04
  • RCT · n = 180
  • Gastroenterology 96(4)
  • • C. Surawicz
    • G. Elmer
    • P. Speelman
    • LynneV. McFarland
    • J. Chinn
    • G. Belle

  • PubMed: 2494098
  • DOI: 10.1016/0016-5085(89)91613-2

  3 Insights on

  • Reduced Diarrhea

  • High evidence
  • Highly Cited

  Of the patients receiving placebo, 22% experienced diarrhea compared with 9.5% of patients receiving S. boulardii (p = 0.038).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Efficacy and Safety of Saccharomyces boulardii in the 14‐day Triple Anti‐Helicobacter pylori Therapy: A Prospective Randomized Placebo‐Controlled Double‐Blind Study

  • 2007-07-30
  • RCT
  • Helicobacter 12(4)
  • • M. Cindoruk
    • Gulbanu Erkan
    • T. Karakan
    • A. Dursun
    • S. Unal

  • PubMed: 17669103
  • DOI: 10.1111/j.1523-5378.2007.00516.x

  5 Insights on

  • Reduced Diarrhea

  • High evidence
  • Highly Cited

  Nine (14.5%) patients in the treatment group and 19 (30.6%) patients in the placebo group experienced diarrhea (p < .05).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  Not stated in abstract