Best Supplements for Reduced Diarrhea
Ranked by research evidence. Compare 28 supplements across 42 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- High evidence9 studies
Across 9 studies, all reported beneficial effects of Saccharomyces boulardii on reducing diarrhea, with effect sizes ranging from small to large (predominantly moderate). Evidence comes primarily from clinical populations, including patients with H. pylori infection, those undergoing pelvic radiotherapy, critically ill tube-fed patients, and hospitalized patients. The most studied dose was 250 mg/day to 500 mg four times daily, and the median study duration was 14 days.
Dose: 250 mg/day to 500 mg four times daily - Low evidence3 studies
Across 3 randomized controlled trials, 1 reported a beneficial small-sized effect of Saccharomyces boulardii on reduced diarrhea, while 2 found neutral effects. The most-studied dose was 500 mg twice daily, and study populations were clinical (patients with SIBO, IBS-D, or undergoing H. pylori eradication). Median study duration was 15 days.
Dose: 500 mg twice daily - Low evidence3 studies
Across 3 studies, 1 reported a beneficial moderate-sized effect on reducing diarrhea symptoms in children with acute diarrhoea, while 2 found neutral effects in healthy children. The predominant effect size across all studies is small. The most-studied population is children (2–5 years and 6–36 months), but the evidence is limited and inconsistent.
Dose: 4 × 10^8 colony-forming units/dayProduct matchBioGaia — Kids, Immune Active with L. Reuteri + Vitamin D, Orange· $26.99 · ★4.8 (510)
- Highsaccharomyces boulardiiAcross 9 studies, all reported beneficial effects of Saccharomyces boulardii on reducing diarrhea, with effect sizes ranging from small to large (predominantly moderate). Evidence comes primarily from clinical populations, including patients with H. pylori infection, those undergoing pelvic radiotherapy, critically ill tube-fed patients, and hospitalized patients. The most studied dose was 250 mg/day to 500 mg four times daily, and the median study duration was 14 days. · Dose: 250 mg/day to 500 mg four times daily9 beneficial9 studies
- LowSaccharomyces boulardiiAcross 3 randomized controlled trials, 1 reported a beneficial small-sized effect of Saccharomyces boulardii on reduced diarrhea, while 2 found neutral effects. The most-studied dose was 500 mg twice daily, and study populations were clinical (patients with SIBO, IBS-D, or undergoing H. pylori eradication). Median study duration was 15 days. · Dose: 500 mg twice daily1 beneficial2 neutral3 studies
- LowLactobacillus reuteri DSM 17938Across 3 studies, 1 reported a beneficial moderate-sized effect on reducing diarrhea symptoms in children with acute diarrhoea, while 2 found neutral effects in healthy children. The predominant effect size across all studies is small. The most-studied population is children (2–5 years and 6–36 months), but the evidence is limited and inconsistent. · Dose: 4 × 10^8 colony-forming units/day1 beneficial2 neutral3 studies