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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Improved Skin Hydration

Ranked by research evidence. Compare 9 supplements across 20 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Low evidence10 studies

    Across 10 studies, 10 reported beneficial effects of Lactobacillus brevis SBC8803 on skin hydration, with effect sizes predominantly small to moderate. The highest-quality evidence comes from a single randomized controlled trial (RCT) with 126 adults showing marginal improvements in transepidermal water loss and corneal hydration, though results were not statistically significant. A meta-analysis of probiotic interventions (including this strain) found a moderate beneficial effect on skin hydration (pSMD = 0.71, p = 0.0026), but doses and populations varied across studies.

9 supplements
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