Best Supplements for Reduced Alkaline Phosphatase Level
Ranked by research evidence. Compare 19 supplements across 22 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence3 studies
Across all 3 studies, beneficial effects of thistle (silymarin) on reducing alkaline phosphatase (ALP) levels were reported, with small to moderate effect sizes. 3 out of 3 studies found statistically significant reductions. The median study duration was 111 days across 2 studies that reported duration, indicating effects typically observed at around 16 weeks. The most studied population was clinical (e.g., breast cancer patients on chemotherapy, patients on antituberculosis drugs).
Dose: 140 mg daily
19 supplements
- ModerateThistleAcross all 3 studies, beneficial effects of thistle (silymarin) on reducing alkaline phosphatase (ALP) levels were reported, with small to moderate effect sizes. 3 out of 3 studies found statistically significant reductions. The median study duration was 111 days across 2 studies that reported duration, indicating effects typically observed at around 16 weeks. The most studied population was clinical (e.g., breast cancer patients on chemotherapy, patients on antituberculosis drugs). · Dose: 140 mg daily3 beneficial3 studies