Best Supplements for Reduced Homocysteine Level
Ranked by research evidence. Compare 9 supplements across 16 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- High evidence6 studies
Across 6 studies, 5 reported beneficial effects on reducing homocysteine levels, with effect sizes ranging from small to large (mixed). The median study duration was 84 days (12 weeks), indicating effects typically observed at that timeframe. Most studies used doses of 400 μg to 1 mg per day in diverse adult populations, including healthy adults, patients with coronary heart disease, and those with type 2 diabetes.
Dose: 400 μg to 1 mg per day
9 supplements
- HighVitamin B9Across 6 studies, 5 reported beneficial effects on reducing homocysteine levels, with effect sizes ranging from small to large (mixed). The median study duration was 84 days (12 weeks), indicating effects typically observed at that timeframe. Most studies used doses of 400 μg to 1 mg per day in diverse adult populations, including healthy adults, patients with coronary heart disease, and those with type 2 diabetes. · Dose: 400 μg to 1 mg per day5 beneficial1 neutral6 studies