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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced Homocysteine Level

Ranked by research evidence. Compare 5 supplements across 7 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Moderate evidence3 studies

    Across 3 studies, 2 reported beneficial effects on reducing homocysteine levels, with effect sizes that were mixed (small to moderate). The available evidence includes a meta-analysis (moderate effect) and a systematic review (small effect), supporting a beneficial effect. The median study duration among the limited reporting studies was 84 days, but dose and form data were insufficient to identify a typical regimen.

    Product match
    MaryRuth OrganicsOrganic Kids Multivitamin Gummies
    200 mcg DFE · $22.99 · ★5.0 (24)
5 supplements
  • ModerateVitamin B9Across 3 studies, 2 reported beneficial effects on reducing homocysteine levels, with effect sizes that were mixed (small to moderate). The available evidence includes a meta-analysis (moderate effect) and a systematic review (small effect), supporting a beneficial effect. The median study duration among the limited reporting studies was 84 days, but dose and form data were insufficient to identify a typical regimen.2 beneficial1 neutral3 studies
  • Lactobacillus acidophilus1 beneficial1 study
  • Vitamin B61 beneficial1 study
  • Vitamin B121 beneficial1 study
  • Buckwheat1 beneficial1 study
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