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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced Probing Pocket Depth

Ranked by research evidence. Compare 29 supplements across 32 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Moderate evidence3 studies

    Across 3 studies, 2 reported beneficial effects (moderate to large) of Lactobacillus reuteri on reducing probing pocket depth, while 1 high-quality RCT found no significant difference from placebo. The most-studied form was lozenges, but specific CFU doses varied. Effects were observed in patients with periodontitis or peri-implantitis over a median duration of 56 days.

    Product match
    Primal HarvestPrimal Probiotics
    250,000,000 CFU · $38.95 · ★5.0 (2)
29 supplements
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