Research synthesisLow evidenceSmall effect3 studies · 3 beneficial · 0 neutral · 0 harmful
Across 3 studies, all reported beneficial effects of Black Cumin (Nigella sativa) on reducing diastolic blood pressure, with effect sizes ranging from small to moderate. The most robust evidence comes from two large meta-analyses, one of which found a small but statistically significant reduction (WMD = -2.75 mmHg). Effects were typically observed over 4–8 weeks, with doses spanning 200–4600 mg/day, though the evidence base is small (only 3 studies).
- Effective dose range: 200 to 4600 mg/day
- Studied populations: patients with metabolic diseases, postmenopausal women with hypertension
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). The only observational study had a small sample size (n=52) and no control group, limiting causal inference.
Generated Jun 4, 2026