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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Flax and Reduced Diastolic Blood Pressure

Research synthesisLow evidenceMixed effect size3 studies · 1 beneficial · 2 neutral · 0 harmful

Across 3 studies, 1 reported a small beneficial effect and 2 reported neutral results. The median study duration was 49 days (4+ weeks). The predominant effect size was mixed (small beneficial and small neutral across studies). The single beneficial study used a dose of 25 mL/day in adults with metabolic syndrome. The evidence base is too small to draw firm conclusions.

  • Effective dose range: 25 mL/day (based on 1 beneficial study)
  • Studied populations: adults with metabolic syndrome

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. The single beneficial RCT had a small sample (n=60); larger meta-analyses found non-significant neutral effects.

Generated Jul 13, 2026
Doses used in studies
  • mL/day: 25 (median 25, IQR 25–25) — 1 study
Time to effect
Median: 7 weeks · IQR 7 weeks–7 weeks · Range 7 weeks–7 weeks — Reported in 1 of 3 studies
3 of 3 papers
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