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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Passion Flower and Reduced Anxiety

Research synthesisModerate evidenceMixed effect size7 studies · 6 beneficial · 1 neutral · 0 harmful

Across 7 studies, 6 reported beneficial effects for reducing anxiety, with effect sizes ranging from small to moderate. 5 of the 6 beneficial studies reached statistical significance. The evidence is most consistent for situational anxiety (e.g., pre-surgery, dental procedures), though many studies combined passion flower with other herbs such as valerian.

  • Studied populations: adults with situational anxiety (e.g., pre-surgery, dental procedures)

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Additionally, many studies combine passion flower with other herbs, making it difficult to isolate its effect. Doses and forms are inconsistently reported.

Generated May 15, 2026
Doses used in studies
  • mg/day: 260 (median 260, IQR 260260) 1 study
Safety in these studies
7 of 7 papers
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