Research synthesisLow evidenceSmall effect3 studies · 2 beneficial · 1 neutral · 0 harmful
Across 3 studies, 2 reported beneficial effects (1 small, 1 moderate) and 1 found neutral results for passion flower in reducing anxiety. The only statistically significant finding came from one small RCT (n=54) showing moderate benefit for dental anxiety. Evidence is preliminary, and the sole higher-quality RCT (n=210) observed a small beneficial effect but did not report significance, with passion flower tested as part of a calming herbal tea blend.
- Studied populations: clinical (elective surgery patients), adults (dental surgery patients)
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. One study tested passion flower as part of a multi-herb blend, making it difficult to isolate the effect of passion flower alone. The neutral study was a review that did not focus exclusively on passion flower. Many studies did not report dose, form, or duration, limiting comparability.
Generated May 14, 2026