St. John's Wort

Safety profile

6 studies reporting safety data2 serious adverse events

Across 6 clinical studies, St. John's Wort was generally described as well tolerated, with no quantitative adverse event findings indicating increased risk compared to control. Two serious adverse events were flagged, including serotonin syndrome risk when combined with other serotonergic agents, and drug interactions involving CYP 450 substrates were noted as safety concerns.

Caveats: Most reports are qualitative and not from controlled safety analyses; studies were often designed for efficacy rather than safety, and long-term safety data are limited. The evidence base is small (6 studies), so the absence of reported adverse events does not establish comprehensive safety.

Most-studied combinations with St. John's Wort

most supplement research is combination research

Also studied with:Passion Flower (2), Lavender (3), Ginkgo (2), Saffron (2)

St. John's Wort Herb
By Nature's Way
4.5 (3.9K reviews)
Out of Stock
Pricing Information
Ingredient St. John's Wort
Amount per Pill 350 mg
Total Amount 126 g
Price per mg USD 0.0001
Supplement Ingredients
Ingredients Amount Per Serving
St. John's Wort
St. John's Wort
700 mg
stem
-
leaf
-
flower
-
Outcomes Supported by Research
Reduced Listeria Monocytogenes Population1 studies
Increased Antibacterial Activity Against Pathogens1 studies
Reduced Virulence / Lower Risk of Fungemia1 studies
Reduced Anti-Listeria Effect1 studies
Reduced Listeria Colonization1 studies
Gluten Free
Sugar Free
Vegan
Non-GMO Project Verified
Product Description
Supports emotional well-being and mood stabilization with 700 mg of St. John's Wort per capsule
Sugar Free to maintain a healthier dietary choice
Gluten Free making it accessible for those with gluten sensitivities
Vegan to cater to plant-based lifestyles and ethical dietary preferences
Verified by the Non-GMO Project, ensuring a product free from genetically modified organisms
Nature's Way St. John's Wort Herb capsules are crafted with purity and efficacy in mind. By offering a gluten-free, sugar-free, and vegan-friendly solution, users can confidently support their mental health without compromising their dietary restrictions. The Non-GMO Project Verification is an additional assurance of the product's natural origins and quality.
Other ingredients
plant-derived capsule (hypromellose)
cellulose
Free of
sugar
salt
yeast
wheat
soy
corn
dairy products
artificial colors
artificial flavors
artificial preservatives
Serving Size: 2
Servings per Container: 90
Pill Type: Capsule
Flavor: -
UPC: 033674140413
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Bye-Lori Plus

By Life Enhancement

4.3 (299 reviews)

Out of Stock

Pricing Information
Ingredient	St. John's Wort
Amount per Pill	83.33 mg
Total Amount	90 g
Price per mg	USD 0.0008

Supplement Ingredients
Ingredients	Amount Per Serving
Vitamin C Vitamin C	19 mg
ascorbyl palmitate Ascorbyl Palmitate	-
Deglycyrrhizinated Licorice (Glycyrrhiza glabra) root Licorice	1.2 g
root	-
mastic gum extract Mastic	1 g
Pistacia lentiscus Mastic	-
turmeric root (Curcuma longa) Turmeric	800 mg
root	-
St. John's wort whole plant extract St. John's Wort	500 mg
Hypericum perforatum St. John's Wort	-
standardized to 3% hyperforin	-
thyme leaf powder Thyme	35 mg
Thymus vulgaris Thyme	-
cinnamon bark powder Cinnamon	10 mg
Cinnamomi cassiae Cinnamon	-

Product Description

Supports digestive health with mastic gum extract (1000 mg), known for its traditional use in managing stomach discomfort.
Enhances mental well-being and mood balance with St. John's wort extract (500 mg).
Boosts immune support and overall vitality with Vitamin C (19 mg).
Promotes a healthy inflammatory response with cinnamon bark powder (10 mg) and turmeric root (800 mg).
Soothes the digestive tract with Deglycyrrhizinated Licorice root (1200 mg), traditionally used for its calming effects.
Provides antioxidant protection and supports immune health with thyme leaf powder (35 mg).
Vegetarian capsules ensure compatibility with a plant-based diet.
Formulated to target and support intestinal health naturally, aligning with the product's primary purpose: "Bye-Lori Plus."

Other ingredients

vegetable capsule

Free of

Serving Size: 6

Servings per Container: 30

Pill Type: Vegetable Capsule

Flavor: -

UPC: 603902100405

St. John's Wort
By Solaray
4.5 (247 reviews)
Out of Stock
Pricing Information
Ingredient St. John's Wort
Amount per Pill 450 mg
Total Amount 90 g
Price per mg USD 0.0002
Supplement Ingredients
Ingredients Amount Per Serving
Organic St. John's Wort (Hypericum perforatum)
St. John's Wort
900 mg
aerial
-
Organic
Vegan
Product Description
Supports emotional balance and mental well-being with 900 mg of organic St. John's Wort per serving.
Contains pure and organic St. John's Wort (Hypericum perforatum), known for its mood-enhancing properties.
Vegan-friendly formulation, ensuring it fits into plant-based lifestyles without compromise.
Utilizes vegetarian capsules, offering a clean, animal-free option for those seeking plant-based supplements.
Solaray ensures the high-quality and purity of ingredients by using organically sourced St. John's Wort.
Designed to naturally support your mood without synthetic additives or preservatives.
Simple and convenient one-capsule daily dosage.
Other ingredients
vegetable cellulose capsule
Free of
-
Serving Size: 2
Servings per Container: 50
Pill Type: Vegetable Capsule
Flavor: -
UPC: 076280195538
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St. John's Wort 450
By Source Naturals
4.5 (244 reviews)
In Stock
Pricing Information
Ingredient St. John's Wort
Amount per Pill 450 mg
Total Amount 81 g
Price per mg USD 0.0003
Supplement Ingredients
Ingredients Amount Per Serving
St. John's Wort extract
St. John's Wort
450 mg
aerial parts
-
standardized extract
-
Outcomes Supported by Research
Reduced Virulence / Lower Risk of Fungemia1 studies
Increased Antibacterial Activity Against Pathogens1 studies
Reduced Listeria Monocytogenes Population1 studies
Immune Response to Rotavirus Vaccine Antigen1 studies
Reduced Anti-Listeria Effect1 studies
Sugar Free
Vegetarian
Product Description
Supports emotional well-being and mental balance with 450 mg of pure St. John's Wort extract per tablet.
Promotes a healthy outlook on life, helping you manage everyday stress and maintain a positive mindset.
Sugar-free formula, making it an ideal choice for those monitoring their sugar intake and looking to maintain healthy blood sugar levels.
Suitable for vegetarians, aligning with a variety of dietary preferences and ethical choices.
Tablets are crafted with high-quality St. John's Wort extract known for its consistent potency and efficacy.
Backed by Source Naturals' commitment to rigorous quality and purity standards, ensuring you receive the best possible supplement for mental and emotional support.
Incorporate Source Naturals St. John's Wort 450 into your daily routine to enjoy the benefits of a balanced mood and emotional well-being, perfectly tailored to fit a sugar-free and vegetarian lifestyle.
Other ingredients
dibasic calcium phosphate
modified cellulose gum
microcrystalline cellulose
stearic acid
silica
magnesium stearate
Free of
yeast
dairy
egg
gluten
soy
wheat
sugar
preservatives
artificial color
artificial flavor
artificial fragrance
Serving Size: 1
Servings per Container: 180
Pill Type: Tablet
Flavor: -
UPC: 021078011774
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St. John's Wort
By NOW Foods
4.5 (1.4K reviews)
Out of Stock
Pricing Information
Ingredient St. John's Wort
Amount per Pill 300 mg
Total Amount 75 g
Price per mg USD 0.0003
Supplement Ingredients
Ingredients Amount Per Serving
St. John's Wort extract
St. John's Wort
300 mg
Hypericum perforatum (herb)
St. John's Wort
-
minimum 0.3% hypericin
St. John's Wort
-
Kosher
Vegan
Vegetarian
GMP Certified
Non-GMO Project Verified
Product Description
Promote emotional well-being with St. John's Wort extract, traditionally used to support a positive mood.
Each vegetarian capsule contains 300 mg of potent St. John's Wort extract for consistent and effective dosing.
Certified Kosher, making it suitable for individuals with specific dietary restrictions.
Vegan-friendly formulation ensures no animal products are used, catering to plant-based lifestyles.
GMP Certified, guaranteeing high-quality and purity standards in every capsule.
Verified Non-GMO, ensuring that ingredients are sourced to meet your health-conscious choices.
Convenient, easy-to-swallow vegetarian capsules offer a reliable and easy way to support your mental health.
Trust NOW Foods, a brand committed to providing top-quality dietary supplements to enhance your overall well-being.
Other ingredients
hypromellose (cellulose capsule)
stearic acid (vegetable source)
silicon dioxide
Free of
wheat
gluten
soy
milk
egg
fish
shellfish
tree nut ingredients
Serving Size: 1
Servings per Container: 250
Pill Type: Vegetable Capsule
Flavor: -
UPC: 733739047618
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St. John's Wort Extract
By Lake Avenue Nutrition
4.6 (3.2K reviews)
In Stock
Pricing Information
Ingredient St. John's Wort
Amount per Pill 300 mg
Total Amount 72 g
Price per mg USD 0.0003
Supplement Ingredients
Ingredients Amount Per Serving
St. John's Wort extract
St. John's Wort
300 mg
Hypericum perforatum (aerial parts)
St. John's Wort
-
standardized to 0.3% hypericin
St. John's Wort
-
Product Description
Supports emotional well-being and a balanced mood with St. John's Wort extract.
Contains 300 mg of high-quality St. John's Wort extract per vegetarian capsule.
Vegetarian capsules are suitable for various dietary preferences.
Helps maintain mental health through natural herbal support.
Known for promoting a positive outlook and mental clarity.
Sustainably sourced ingredients ensure ethical production.
Expertly formulated for optimal assimilation and benefits.
Other ingredients
microcrystalline cellulose
modified cellulose (hypromellose veggie capsule)
dextrin (carrier for St. John's Wort extract)
silicon dioxide (silica)
stearic acid
Free of
milk
eggs
fish
crustacean shellfish
tree nuts
peanuts
wheat
soy
sesame
gluten
Serving Size: 1
Servings per Container: 240
Pill Type: Vegetable Capsule
Flavor: -
UPC: 898220017904
Available From
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Merchant Price Stock Action
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$19.06
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St. John's Wort Herb
By Nature's Way
4.5 (3.9K reviews)
In Stock
St. John's Wort
By Nutricost
4.6 (84 reviews)
Out of Stock
EuroHerbs
By California Gold Nutrition
4.5 (4.1K reviews)
Out of Stock
Standardized St. John's Wort
By Nature's Truth
4.8 (14 reviews)
Out of Stock
St. John's Wort Vital Extracts
By Solaray
4.6 (108 reviews)
In Stock
St. John's Wort
By Vital Nutrients
Out of Stock
Mood Support with St. John's Wort
By NOW Foods
4.5 (5.6K reviews)
Out of Stock
St. John's Wort
By Healths Harmony
4.5 (53 reviews)
In Stock
Vital Extracts
By Solaray
4.9 (9 reviews)
Out of Stock
St. Johns's Wort Extract
By Swanson
4.7 (188 reviews)
Out of Stock
St. John's Wort
By NOW Foods
4.5 (1.4K reviews)
In Stock
St. John's Wort
By Nature's Bounty
4.7 (507 reviews)
In Stock
Full Spectrum St. John's Wort Extract
By Planetary Herbals
4.6 (190 reviews)
Out of Stock
St. John's Wort Extract
By Lake Avenue Nutrition
4.6 (3.3K reviews)
Out of Stock
Vital Extracts
By Solaray
4.6 (110 reviews)
In Stock
Herbal Actives
By NaturesPlus
4.6 (133 reviews)
In Stock
St. John's Wort
By MRM Nutrition
4.5 (358 reviews)
Out of Stock
St. John's Wort
By Nature's Way
4.5 (174 reviews)
In Stock
St. John's Wort
By Paradise Herbs
4.3 (128 reviews)
In Stock
EstroPause
By Irwin Naturals
4.6 (602 reviews)
Out of Stock
HTP Calm
By Natural Balance
4.1 (42 reviews)
In Stock
Perika
By Nature's Way
4.4 (659 reviews)
Out of Stock
EuroHerbs
By California Gold Nutrition
4.5 (4.1K reviews)
Out of Stock
Standardized Extract
By Mason Natural
4.6 (38 reviews)
In Stock

Ingredients	Amount Per Serving
Organic St. John's Wort (Hypericum perforatum) St. John's Wort	900 mg
aerial	-

Ingredients	Amount Per Serving
St. John's Wort extract St. John's Wort	450 mg
aerial parts	-
standardized extract	-

Ingredients	Amount Per Serving
St. John's Wort extract St. John's Wort	300 mg
Hypericum perforatum (herb) St. John's Wort	-
minimum 0.3% hypericin St. John's Wort	-

Ingredients	Amount Per Serving
St. John's Wort extract St. John's Wort	300 mg
Hypericum perforatum (aerial parts) St. John's Wort	-
standardized to 0.3% hypericin St. John's Wort	-

Available From
Merchant	Price	Stock
Amazon	$-	Out
iHerb	$14.31	In
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Available From
Merchant	Price	Stock
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iHerb	$72.70	In
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Available From
Merchant	Price	Stock
Amazon	$-	Out
iHerb	$17.49	In
Vitacost	$-	Out
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Available From
Merchant	Price	Stock
Amazon	$-	Out
iHerb	$22.79	In
Vitacost	$-	Out
Vitamin Shoppe	$-	Out

St. John's Wort

Safety profile

St. John's Wort Herb

Bye-Lori Plus

St. John's Wort

St. John's Wort 450

St. John's Wort

St. John's Wort Extract

St. John's Wort Herb

St. John's Wort

EuroHerbs

Standardized St. John's Wort

St. John's Wort Vital Extracts

St. John's Wort

Mood Support with St. John's Wort

St. John's Wort

Vital Extracts

St. Johns's Wort Extract

St. John's Wort

St. John's Wort

Full Spectrum St. John's Wort Extract

St. John's Wort Extract

Vital Extracts

Herbal Actives

St. John's Wort

St. John's Wort

St. John's Wort

EstroPause

HTP Calm

Perika

EuroHerbs

Standardized Extract