Bifidobacterium longum MAK34B12L and Reduced LDL Cholesterol

• Bifidobacterium longum with Fructo-Oligosaccharides in Patients with Non Alcoholic Steatohepatitis

  • 2011-09-08
  • RCT · n = 66
  • Digestive Diseases and Sciences 57(2)
  • • M. Malaguarnera
    • M. Vacante
    • T. Antić
    • M. Giordano
    • G. Chisari
    • R. Acquaviva
    • S. Mastrojeni
    • G. Malaguarnera
    • A. Mistretta
    • G. Volti
    • F. Galvano

  • PubMed: 21901256
  • DOI: 10.1007/s10620-011-1887-4

  17 Insights on

  • Reduced LDL Cholesterol

  • High evidence
  • Highly Cited
  • Rigorous Journal

  At the end of study period, we observed that the Bifidobacterium longum with Fos and lifestyle modification group versus the lifestyle modification alone group showed significant differences in LDL cholesterol -0.84 versus -0.18 mmol/L (P < 0.001)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Effects of milk products fermented by Bifidobacterium longum on blood lipids in rats and healthy adult male volunteers.

  • 2003-07
  • RCT · n = 32
  • Journal of Dairy Science 86(7)
  • • J. Xiao
    • S. Kondo
    • N. Takahashi
    • K. Miyaji
    • K. Oshida
    • A. Hiramatsu
    • K. Iwatsuki
    • S. Kokubo
    • A. Hosono

  • PubMed: 12906063
  • DOI: 10.3168/JDS.S0022-0302(03)73839-9

  15 Insights on

  • Reduced LDL Cholesterol

  • High evidence
  • Highly Cited

  The bifidobacterium milk feeding brought about significant lowering of the serum concentrations of total cholesterol, low-density lipoprotein cholesterol.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Hypocholesterolemic effect of sonication-killed Bifidobacterium longum isolated from healthy adult Koreans in high cholesterol fed rats

  • 2010-09
  • RCT · n = 24
  • Archives of Pharmacal Research 33(9)
  • • H. Shin
    • Shin‐Young Park
    • Do Kyung Lee
    • S. A. Kim
    • H. An
    • Jung Rae Kim
    • M. J. Kim
    • Min Gyeong Cha
    • S. Lee
    • Kyung Joo Kim
    • K. Lee
    • N. Ha

  • PubMed: 20945142
  • DOI: 10.1007/s12272-010-0917-7

  14 Insights on

  • Reduced LDL Cholesterol

  • Low evidence
  • Highly Cited
  • Animal Study

  total and LDL-cholesterol levels in the serum were significantly (p < 0.05) less increased in HCKB (total: 177.71 mg/dL, LDL-: 60.50 mg/dL) rats when compared to HCS (total: 237.17 mg/dL, LDL-: 71.50 mg/dL) rats.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes