Bifidobacterium longum MAK34B12L and Reduced Total Cholesterol Levels

• Effects of milk products fermented by Bifidobacterium longum on blood lipids in rats and healthy adult male volunteers.

  • 2003-07
  • RCT · n = 32
  • Journal of Dairy Science 86(7)
  • • J. Xiao
    • S. Kondo
    • N. Takahashi
    • K. Miyaji
    • K. Oshida
    • A. Hiramatsu
    • K. Iwatsuki
    • S. Kokubo
    • A. Hosono

  • PubMed: 12906063
  • DOI: 10.3168/JDS.S0022-0302(03)73839-9

  15 Insights on

  • Reduced Total Cholesterol Levels

  • High evidence
  • Highly Cited

  The bifidobacterium milk feeding brought about significant lowering of the serum concentrations of total cholesterol.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Oral Probiotic Bifidobacterium Longum Supplementation Improves Metabolic Parameters and Alters the Expression of the Renin-Angiotensin System in Obese Mice Liver

  • 2020-07-23
  • RCT · n = 32
  • Biological Research For Nursing 23(1)
  • • A. S. Machado
    • J. R. Oliveira
    • D. F. Lelis
    • A. D. de Paula
    • A. Guimarães
    • J. Andrade
    • I. Brandi
    • S. Santos

  • PubMed: 32700545
  • DOI: 10.1177/1099800420942942

  6 Insights on

  • Reduced Total Cholesterol Levels

  • Low evidence
  • Animal Study

  The treatment also resulted in reduced levels of total cholesterol.

  Effect

  Beneficial

  Effect size

  Moderate

• Hypocholesterolemic effect of sonication-killed Bifidobacterium longum isolated from healthy adult Koreans in high cholesterol fed rats

  • 2010-09
  • RCT · n = 24
  • Archives of Pharmacal Research 33(9)
  • • H. Shin
    • Shin‐Young Park
    • Do Kyung Lee
    • S. A. Kim
    • H. An
    • Jung Rae Kim
    • M. J. Kim
    • Min Gyeong Cha
    • S. Lee
    • Kyung Joo Kim
    • K. Lee
    • N. Ha

  • PubMed: 20945142
  • DOI: 10.1007/s12272-010-0917-7

  14 Insights on

  • Reduced Total Cholesterol Levels

  • Low evidence
  • Highly Cited
  • Animal Study

  total and LDL-cholesterol levels in the serum were significantly (p < 0.05) less increased in HCKB (total: 177.71 mg/dL, LDL-: 60.50 mg/dL) rats when compared to HCS (total: 237.17 mg/dL, LDL-: 71.50 mg/dL) rats.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes