Across 11 studies, all reported beneficial effects of Lactobacillus acidophilus L-92 for reducing allergic symptoms, with moderate effect sizes observed most frequently. The available evidence is composed entirely of review articles, and no statistically significant individual study findings were reported. The most studied populations include individuals with cedar pollen allergy, atopic dermatitis, and allergic rhinitis, but specifics on dose, duration, and form were not consistently reported.
Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. Evidence base consists entirely of review articles with no primary RCT data providing explicit statistical significance, effect sizes, or dosing details, limiting confidence in the findings.
Lactobacillus acidophilus L-92 has been reported to suppress allergic responses and improve symptoms in subjects with cedar pollen allergy, atopic dermatitis, and allergic rhinitis.
Lactobacillus acidophilus L-92 has been reported to improve subjective symptoms in patients with pollen allergies and to reduce the severity of atopic dermatitis in some studies.
oral administration of Lactobacillus acidophilus L-92 can alleviate clinical symptoms of patients with atopic dermatitis and cedar pollinosis
Lactic acid bacteria, especially Lactobacillus acidophilus L-92, have been shown to improve symptoms of allergic diseases in clinical studies.
the wide application of AI-2-mediated interspecific communication in various fields including host health...
Lactobacillus acidophilus L-92 has been reported to alleviate symptoms of pollen allergy, atopic dermatitis, and house dust mite allergy in human clinical studies.
Lactobacillus acidophilus L-92 is reported to have various immune regulatory and anti-allergic effects
Consumption of Lactobacillus acidophilus L-92 has been reported to alleviate symptoms of allergic diseases, including atopic dermatitis and allergic rhinitis.
Consuming Lactobacillus acidophilus L-92 has been reported in research to alleviate symptoms of allergy and improve quality of life in individuals with allergic conditions.
To study the anti-allergy effects of probiotic Lactobacillus acidophilus L-92 (L-92)...
Transcriptome analysis showed that Lactobacillus acidophilus L-92 cells having anti-allergy effects on human up-regulated 41 genes involved permease, ABC transporter, proteinase and transcriptional regulator after attached to epithelial Caco-2 cells.