Across 11 studies, all reported beneficial effects, with most indicating moderate-sized improvements in allergic symptoms. The evidence consistently supports a beneficial effect of Lactobacillus acidophilus L-92 on allergic conditions such as allergic rhinitis, atopic dermatitis, and cedar pollinosis, but no studies provided extractable data on dose, population, or statistical significance.
Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. All 11 studies are review articles, with no primary RCTs or extractable data on dose, duration, sample size, or population. Evidence base relies entirely on secondary sources.
Lactobacillus acidophilus L-92 has been reported to suppress allergic responses and improve symptoms in subjects with cedar pollen allergy, atopic dermatitis, and allergic rhinitis.
Lactobacillus acidophilus L-92 has been reported to improve subjective symptoms in patients with pollen allergies and to reduce the severity of atopic dermatitis in some studies.
oral administration of Lactobacillus acidophilus L-92 can alleviate clinical symptoms of patients with atopic dermatitis and cedar pollinosis
Lactic acid bacteria, especially Lactobacillus acidophilus L-92, have been shown to improve symptoms of allergic diseases in clinical studies.
the wide application of AI-2-mediated interspecific communication in various fields including host health...
Lactobacillus acidophilus L-92 has been reported to alleviate symptoms of pollen allergy, atopic dermatitis, and house dust mite allergy in human clinical studies.
Lactobacillus acidophilus L-92 is reported to have various immune regulatory and anti-allergic effects
Consumption of Lactobacillus acidophilus L-92 has been reported to alleviate symptoms of allergic diseases, including atopic dermatitis and allergic rhinitis.
Consuming Lactobacillus acidophilus L-92 has been reported in research to alleviate symptoms of allergy and improve quality of life in individuals with allergic conditions.
To study the anti-allergy effects of probiotic Lactobacillus acidophilus L-92 (L-92)...
Transcriptome analysis showed that Lactobacillus acidophilus L-92 cells having anti-allergy effects on human up-regulated 41 genes involved permease, ABC transporter, proteinase and transcriptional regulator after attached to epithelial Caco-2 cells.