Lactobacillus fermentum MAK20L13F and Improved Lipid Profile

• Oral administration of Lactobacillus fermentum CRL1446 improves biomarkers of metabolic syndrome in mice fed a high-fat diet supplemented with wheat bran.

  • 2021-03-23
  • Clinical Trial · n = 6
  • Food & Function 11(5)
  • • R. Medina
    • Matías Russo
    • Antonela Marquez
    • Héctor M. Herrera
    • M. C. Abeijón-Mukdsi
    • L. Saavedra
    • E. Hebert
    • Paola Gauffin-Cano

  • PubMed: 32421119
  • DOI: 10.1039/d0fo00730g

  26 Insights on

  • Improved Lipid Profile

  • Low evidence
  • Animal Study

  ...improvement of inflammatory profile, reduction of fatty infiltration in hepatocytes and modification of lipid profile (increased HDL-cholesterol and decreased LDL-cholesterol and triglyceride levels) were observed.

  Effect

  Beneficial

  Effect size

  Moderate

• The probiotic Lactobacillus fermentum 296 attenuates cardiometabolic disorders in high fat diet-treated rats.

  • 2019-12
  • Nutrition, Metabolism and Cardiovascular Diseases 29(12)
  • • R. G. S. Cavalcante
    • Thatyane Mariano Rodrigues de Albuquerque
    • M. O. de Luna Freire
    • Georgianna de Araújo Henriques Ferreira
    • L. A. Carneiro dos Santos
    • M. Magnani
    • J. Cruz
    • V. Braga
    • E. L. de Souza
    • J. L. de Brito Alves

  • PubMed: 31640890
  • DOI: 10.1016/J.NUMECD.2019.08.003

  10 Insights on

  • Improved Lipid Profile

  • Low evidence

  The administration of L. fermentum 296 for 4 weeks... alleviated hyperlipidemia...

  Effect

  Beneficial

  Effect size

  Moderate

• Characterisation of Lactobacillus fermentum SM-7 isolated from koumiss, a potential probiotic bacterium with cholesterol-lowering effects.

  • 2010-10-28
  • Clinical Trial
  • Journal of the Science of Food and Agriculture 91(3)
  • • D. Pan
    • Xiaoqun Zeng
    • Yuhua Yan

  • PubMed: 21218486
  • DOI: 10.1002/jsfa.4214

  18 Insights on

  • Improved Lipid Profile

  • Low evidence
  • Highly Cited
  • Animal Study

  In vivo experiments using L. fermentum SM-7 on artificially induced hyperlipidaemial ICR mice significantly decreased serum total cholesterol and total triglyceride levels, low-density lipoprotein cholesterol concentrations and atherogenic index (P < 0.01)...

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes