Lactobacillus gasseri BNR17 and Reduced Hip Circumference

Research synthesisLow evidenceSmall effect3 studies · 2 beneficial · 1 neutral · 0 harmful

Across 3 studies, 2 reported beneficial small-sized effects of Lactobacillus gasseri BNR17 on reducing hip circumference in obese adults. The only reported dose was 10^10 CFU/day. Evidence is preliminary due to the small number of studies.

Studied populations: obese adults

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Only one study reported a specific dose (10^10 CFU/day), and study durations were not consistently reported, limiting the ability to determine optimal dosing and treatment duration.

Generated Jul 12, 2026

Doses used in studies

CFU/day: 10 billion (median 10 billion, IQR 10 billion–10 billion) — 1 study

Safety in these studies

Overall tolerabilityReported
The two groups had no special or severe adverse reactions.
from: Effect of Lactobacillus gasseri BNR17 on Overweight and Obese Adults: A Randomized, Double

3 of 3 papersPopulation:

Effect of Lactobacillus gasseri BNR17 on Overweight and Obese Adults: A Randomized, Double-Blind Clinical Trial
- 2013-04-08
- RCT · n = 62
- Korean Journal of Family Medicine 34(2)
- - Seung-Pil Jung
  - Keun-Mi Lee
  - Ji-hee Kang
  - S. Yun
  - Han-Oh Park
  - Yong Moon
  - Jong-Yeon Kim
- PubMed: 23560206
- DOI: 10.4082/kjfm.2013.34.2.80
5 Insights on
- Reduced Hip Circumference
- High evidence
- Highly Cited
- Adults
Decrease of waist and hip circumferences in the BNR17 group was more pronounced than those in the placebo group.
Effect
Beneficial
Effect size
Small
Significant
Yes
Probiotic Lactobacillus sp. as a strategy for modulation of non-comorbid obesity: A systematic meta-analysis and GRADE assessment of randomized controlled trials.
- 2025-04-23
- Meta-Analysis · n = 58
- Narra J 5(2)
- - Juan Ajmn Lele
  - Karlos B Sihaloho
  - Dewa Vighneshwara
  - Derren Dch Rampengan
  - Chrisandi Y Rizqiansyah
  - Happy K Permatasari
  - Nelly Mayulu
  - Trina E Tallei
  - Nurpudji A Taslim
  - Bonglee Kim
  - Immanuelle Kezia
  - Fahrul Nurkolis
  - Rony A Syahputra
- PubMed: 40951500
- DOI: 10.52225/narra.v5i2.1562
9 Insights on
- Reduced Hip Circumference
- High evidence
... and hip circumference (MD: -0.85 cm; 95%CI: -1.09-(-0.61), p<0.00001)
Effect
Beneficial
Effect size
Small
Significant
Yes
Lactobacillus gasseri BNR17 Supplementation Reduces the Visceral Fat Accumulation and Waist Circumference in Obese Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
- 2018-05
- RCT · n = 90
- Journal of Medicinal Food 21(5)
- - Joohee Kim
  - J. Yun
  - M. K. Kim
  - O. Kwon
  - B. Cho
- PubMed: 29688793
- DOI: 10.1089/jmf.2017.3937
12 Insights on
- Reduced Hip Circumference
- High evidence
- Highly Cited
- Clinical
Body weight, BMI, waist and hip circumferences, waist-to-hip ratio, abdominal adipose tissue areas, body fat mass, lean body mass, and biochemical parameters were assessed... Biochemical parameters were not significantly different among the groups.
Effect
Neutral
Effect size
Small
Significant
No
Dose
10^10 CFU/day

Lactobacillus gasseri BNR17 and Reduced Hip Circumference

Effect of Lactobacillus gasseri BNR17 on Overweight and Obese Adults: A Randomized, Double-Blind Clinical Trial

Probiotic Lactobacillus sp. as a strategy for modulation of non-comorbid obesity: A systematic meta-analysis and GRADE assessment of randomized controlled trials.

Lactobacillus gasseri BNR17 Supplementation Reduces the Visceral Fat Accumulation and Waist Circumference in Obese Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.