Across 3 studies, all reported beneficial effects of Lactobacillus gasseri BNR17 on reduced waist circumference, with effect sizes ranging from small to moderate. Two of the three studies reported statistically significant reductions, including a meta-analysis showing a mean difference of -1.41 cm. The evidence is derived from obese adult populations, though dose and study duration were not consistently reported.
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed).
The two groups had no special or severe adverse reactions.
from: Effect of Lactobacillus gasseri BNR17 on Overweight and Obese Adults: A Randomized, DoubleDecrease of waist and hip circumferences in the BNR17 group was more pronounced than those in the placebo group.
Significant reductions were observed in ... waist circumference (MD: -1.41 cm; 95%CI: -1.75-(-1.08), p<0.00001)
Waist circumferences were significantly decreased in both the BNR-L and BNL-H groups (P = .045 and .012, respectively) compared with the baseline values, but not in the placebo group.