Lactobacillus salivarius UALb-07 and Reduced Probing Depth

• Improvement of periodontal condition by probiotics with Lactobacillus salivarius WB21: a randomized, double-blind, placebo-controlled study.

  • 2008-09-12
  • RCT · n = 66
  • Journal of Clinical Periodontology 35(10)
  • • H. Shimauchi
    • G. Mayanagi
    • S. Nakaya
    • Maiko Minamibuchi
    • Yasuhiro Ito
    • K. Yamaki
    • H. Hirata

  • PubMed: 18727656
  • DOI: 10.1111/j.1600-051X.2008.01306.x

  8 Insights on

  • Reduced Probing Depth

  • High evidence
  • Highly Cited
  • Adults

  Current smokers in the test group showed a significantly greater improvement of plaque index and probing pocket depth from BL when compared with those in the placebo group.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Lactobacillus salivarius WB21--containing tablets for the treatment of oral malodor: a double-blind, randomized, placebo-controlled crossover trial.

  • 2014-04
  • RCT
  • Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 117(4)
  • • N. Suzuki
    • M. Yoneda
    • Kazunari Tanabe
    • A. Fujimoto
    • Kosaku Iha
    • K. Seno
    • Kazuhiko Yamada
    • T. Iwamoto
    • Y. Masuo
    • T. Hirofuji

  • PubMed: 24556493
  • DOI: 10.1016/j.oooo.2013.12.400

  6 Insights on

  • Reduced Probing Depth

  • High evidence

  In contrast, the concentration of volatile sulfur compounds (VSCs) (P = .019) and the average probing pocket depth (P = .001) decreased significantly in the probiotic period compared with the placebo period.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes