Lactobacillus salivarius UALs07 and Improved Immune Response

• Intestinal and immunological effects of daily oral administration of Lactobacillus salivarius CECT5713 to healthy adults.

  • 2010-06
  • RCT · n = 40
  • Anaerobe 16(3)
  • • S. Sierra
    • F. Lara‐Villoslada
    • Lluis Sempere
    • M. Olivares
    • J. Boza
    • J. Xaus

  • PubMed: 20159049
  • DOI: 10.1016/j.anaerobe.2010.02.001

  7 Insights on

  • Improved Immune Response

  • High evidence
  • Highly Cited

  Probiotic treatment induced significantly the percentage of NK cells and monocytes, as well as the plasmatic levels of immunoglobulins M, A and G, and the regulatory cytokine IL-10 (72.3+/-11.7 in probiotic group vs. 27.3+/-6.4 pg/mL in control group, P<0.01).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Assessment of Probiotic Properties of Lactobacillus salivarius Isolated From Chickens as Feed Additives

  • 2020-07-17
  • RCT
  • Frontiers in Veterinary Science 7
  • • Jian Wang
    • M. Ishfaq
    • Yuesheng Guo
    • Chunli Chen
    • Jichang Li

  • PubMed: 32766298
  • DOI: 10.3389/fvets.2020.00415

  12 Insights on

  • Improved Immune Response

  • Low evidence
  • Animal Study

  Lactobacillus salivarius results in enhanced immune response after IBDV vaccine immunization, enhanced specific antibody and IFN-γ production, and lymphocyte proliferation.

  Effect

  Beneficial

  Effect size

  Large

• Differential intestinal anti-inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and microbiota composition.

  • 2017-08-29
  • RCT · n = 10
  • Molecular Nutrition & Food Research 61(11)
  • • A. Rodríguez‐Nogales
    • F. Algieri
    • J. Garrido-Mesa
    • T. Vezza
    • M. P. Utrilla
    • N. Chueca
    • Federico García
    • M. Olivares
    • M. Rodríguez-Cabezas
    • J. Gálvez

  • PubMed: 28752563
  • DOI: 10.1002/mnfr.201700144

  12 Insights on

  • Improved Immune Response

  • Low evidence
  • Highly Cited
  • Animal Study

  Both probiotics ameliorated macroscopic colonic damage. They improved the colonic expression of markers involved in the immune response, and the expression of miR-155 and miR-223.

  Effect

  Beneficial

  Effect size

  Moderate