Lactobacillus salivarius UALs07 and Increased Interleukin-10 Levels

• Intestinal and immunological effects of daily oral administration of Lactobacillus salivarius CECT5713 to healthy adults.

  • 2010-06
  • RCT · n = 40
  • Anaerobe 16(3)
  • • S. Sierra
    • F. Lara‐Villoslada
    • Lluis Sempere
    • M. Olivares
    • J. Boza
    • J. Xaus

  • PubMed: 20159049
  • DOI: 10.1016/j.anaerobe.2010.02.001

  7 Insights on

  • Increased Interleukin-10 Levels

  • High evidence
  • Highly Cited

  and the regulatory cytokine IL-10 (72.3+/-11.7 in probiotic group vs. 27.3+/-6.4 pg/mL in control group, P<0.01).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Administration of Lactobacillus salivarius LI01 or Pediococcus pentosaceus LI05 improves acute liver injury induced by d-galactosamine in rats

  • 2014-03-18
  • Clinical Trial
  • Applied Microbiology and Biotechnology 98(12)
  • • L. Lv
    • Xin-Jun Hu
    • Guiyun Qian
    • Hua Zhang
    • H. Lu
    • Bei-wen Zheng
    • Li Jiang
    • Lan-Juan Li

  • PubMed: 24639205
  • DOI: 10.1007/s00253-014-5638-2

  8 Insights on

  • Increased Interleukin-10 Levels

  • Low evidence
  • Animal Study

  The results indicated that pretreatment with L. salivarius LI01 or P. pentosaceus LI05... increased the serum level of interleukin 10 and/or interferon-γ.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes