Research synthesisVery low evidenceSmall effect5 studies · 5 beneficial · 0 neutral · 0 harmful
Across 5 studies (all reviews), all reported beneficial effects of Lactobacillus salivarius UCC118 on immune function, though effect sizes were predominantly small (3 small, 1 moderate, 1 small). No study reported doses, durations, or statistical significance. The evidence is limited to mechanistic and general probiotic reviews rather than dedicated clinical trials.
Caveats: Evidence base is small (only 5 studies) — conclusions should be considered preliminary. All included studies are narrative reviews, not original clinical trials, so effect sizes are qualitative and non-quantifiable. None of the studies reported statistical significance, dosing, or study durations. The beneficial findings may reflect general probiotic properties rather than specific effects of this strain.
Generated Jun 11, 2026